Results 111 to 120 of about 181,131 (286)

A double-blinded randomised controlled trial exploring the effect of anodal transcranial direct current stimulation and uni-lateral robot therapy for the impaired upper limb in sub-acute and chronic stroke [PDF]

, 2015
BACKGROUND:Neurorehabilitation technologies such as robot therapy (RT) and transcranial Direct Current Stimulation (tDCS) can promote upper limb (UL) motor recovery after stroke.
A. Hughes, Aprile, Basteris, Bolognini, Brunoni, Connelly, Dimyan, Dobkin, Duncan, Eriksson, Folstein, Fritsch, Fugl-Meyer, G. Verheyden, Gladstone, Hesse, Hesse, Hesse, Housman, Hummel, J. Rothwell, J.H. Burridge, Khedr, Kim, Klamroth-Marganska, Klem, Krakauer, Kwakkel, Kwakkel, L. Tedesco Triccas, Langhorne, Lee, Levin, Liebetanz, Lindenberg, Lo, Lum, Lyle, M. Desikan, Mehrholz, Nair, Nitsche, Nitsche, Nudo, O’Dell, Page, Platz, Prange, Saghaei, Stagg, Tanaka, Toni, Uswatte, Viana, Vines, Wagner, Wagner, Wu, Ziemann   +58 more
core   +2 more sources

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source

Does cognitive impairment impact adherence? A systematic review and meta-analysis of the association between cognitive impairment and medication non-adherence in stroke.

PLoS ONE, 2017
BackgroundWhile medication adherence is essential for the secondary prevention of stroke, it is often sub-optimal, and can be compromised by cognitive impairment.
Daniela Rohde, Niamh A Merriman, Frank Doyle, Kathleen Bennett, David Williams, Anne Hickey   +5 more
doaj   +1 more source

Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial [PDF]

, 2019
Background: Given the global increase in the aging population and age-related diseases, the promotion of healthy aging is one of the most crucial public health issues.
Benson, Gloria, Buchert, Ralph, Flöel, Agnes, Grittner, Ulrike, Hetzer, Stefan, Horn, Nora, Kopp, Ute, Köbe, Theresa, Lange, Catharina, Madeo, Frank, Maglione, Marta, Mai, Knut, Michael, Eva, Märschenz, Stefanie, Schmitz, Dietmar, Schwarz, Claudia, Sigrist, Stephan J., Stekovic, Slaven, Wirth, Miranka   +18 more
core   +2 more sources

Unilateral Ankle‐Foot Exoneuromusculoskeleton with Balance‐Sensing Feedback for Self‐Help Telerehabilitation after Stroke

Advanced Robotics Research, EarlyView.
This study introduces a hybrid robot that integrates mechanical assistance by musculoskeletons (i.e., soft pneumatic muscle with rigid exoskeletal extensions), neuromuscular electrical stimulation, and vibrotactile feedback in a lightweight wearable mechatronic complex applicable to the paretic ankle–foot poststroke for gait restoration. The system can
Fuqiang Ye, Wei Rong, Waiming Li, Kwok‐Ting Wong, Man‐Kit Pang, Hon‐Wah Wai, Lilly Li, Zicong Hong, Song Guo, Zong‐Hao Ma, Yongping Zheng, Ming Zhang, Nicholas Chow, Jianing Zhang, Xiaoling Hu, Fei Chen, Waisang Poon   +16 more
wiley   +1 more source

Vascular dementia: Current concepts and nomenclature harmonization. [PDF]

, 2012
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core  

Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]

, 2015
Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Rehabilitative devices for a top-down approach [PDF]

, 2019
In recent years, neurorehabilitation has moved from a "bottom-up" to a "top down" approach. This change has also involved the technological devices developed for motor and cognitive rehabilitation.
de Bartolo, Daniela, Di Iulio, Fulvia, Ghanbari Ghooshchy, Sheida, Iosa, Marco, Morone, Giovanni, Paolucci, Stefano, Spitoni, Grazia Fernanda, Zoccolotti, Pierluigi   +7 more
core   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source