Results 141 to 150 of about 231,718 (342)

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. [PDF]

, 2019
Cognitive deficits are a devastating neurological outcome seen in survivors of cardiac arrest. We previously reported water electrolysis derived 67% hydrogen gas inhalation has some beneficial effects on short-term outcomes in a rat model of global brain
Alexander, Bahjat, Bell, Chan, Cohan, Cui, Cui, Ge, Guo, Hayashida, Hayashida, Huang, Huang, Ji, Katsumata, Li, Lim, Moulaert, Nagatani, Neigh, Ohsawa, Ono, Reis, Roine, Schuhmann, Sugawara, Tamura, Tamura, Tian, Volpe, Wang, Xie, Zhao   +32 more
core   +2 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

An occupational therapy intervention for residents with stroke related disabilities in UK care homes (OTCH): cluster randomised controlled trial [PDF]

, 2015
Objective To evaluate the clinical efficacy of an established programme of occupational therapy in maintaining functional activity and reducing further health risks from inactivity in care home residents living with stroke sequelae.
Barton, Garry, Burton, C. R., Burton, Christopher R., Fletcher-Smith, J., Fletcher-Smith, Joanna, Irvine, L., Irvine, Lisa, Lett, K., Mant, J., Mant, Jonathan, Masterson-Algar, Patricia, Peryer, G., Peryer, Guy, Rashid, Farzana, Roalfe, A. K., Roalfe, Andrea K., Sackley, Catherine M., Sharp, L., Sharp, Leslie, Sheehan, B., Sheehan, Bart, Stant, K. E., Stant, Katie E., Steel, Kerry, Steele, K., Walker, M. F., Walker, Marion F., Watkins, C. L., Watkins, Caroline L., Wheatley, K., Wheatley, Keith, Wilde, K., Wilde, Kate, Williams, Jane   +33 more
core   +5 more sources

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

Functional assessment for acute stroke trials: properties, analysis, and application [PDF]

, 2018
A measure of treatment effect is needed to assess the utility of any novel intervention in acute stroke. For a potentially disabling condition such as stroke, outcomes of interest should include some measure of functional recovery.
Dawson, Jesse, Quinn, Terence J., Taylor-Rowan, Martin, Wilson, Alastair   +3 more
core   +2 more sources

Electroacupuncture alleviates post-stroke cognitive impairment through inhibiting miR-135a-5p/mTOR/NLRP3 axis-mediated autophagy.

Neuroscience
Post-stroke cognitive impairment is a significant challenge with limited treatment options. Electroacupuncture (EA) has shown promise in improving cognitive function after stroke. Our study explores the underlying mechanism of EA in alleviating cognitive
Jianchang Luo, Jiawang Lang, Wenbin Xu, Luodan Wang, Zhipeng Zhao, Jie Jia, Boxu Lang   +6 more
semanticscholar   +1 more source

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

Update on the mechanism of microglia involvement in post-stroke cognitive impairment

Frontiers in Aging Neuroscience
Post-stroke cognitive impairment (PSCI) is a clinical syndrome characterized by cognitive deficits that manifest following a stroke and persist for up to 6 months post-event.
Tianxiang Zeng, Jun Liu, Wenjun Zhang, Yanyan Yu, Xinyun Ye, Qianliang Huang, Peng Li, Qiuhua Jiang   +7 more
semanticscholar   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Deficits of knowledge versus executive control in semantic cognition: Insights from cued naming [PDF]

, 2007
Deficits of semantic cognition in semantic dementia and in aphasia consequent on CVA (stroke) are qualitatively different. Patients with semantic dementia are characterised by progressive degradation of central semantic representations, whereas ...
Baayen, Berthier, Bozeat, Burgess, Burgess, Chertkow, Crutch, Damasio, Damasio, Dell, Dell, Demb, Elizabeth Jefferies, Folstein, Forde, Foygel, Funnell, Gloor, Gold, Goodglass, Graham, Hart, Hodges, Howard, Jefferies, Jefferies, Jefferies, Jefferies, Kaplan, Karalyn Patterson, Kay, Lambon Ralph, Lambon Ralph, Lambon Ralph, Lambon Ralph, Martin, Matthew A. Lambon Ralph, Milner, Mummery, Myers Pease, Nestor, Parker, Patterson, Peers, Podraza, Raven, Robertson, Robinson, Robinson, Rogers, Saffran, Saygin, Schwartz, Snodgrass, Snowden, Stuss, Thompson-Schill, Thompson-Schill, Wagner, Warrington, Warrington, Wechsler, Wernicke   +62 more
core   +3 more sources