Results 121 to 130 of about 571,207 (361)

Data from Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma

, 2023
Irena Misiewicz-Krzemińska, María Eugenia Sarasquete, Carolina Vicente‐Dueñas, Patryk Krzemiński, Katarzyna Wiktorska, Luís A. Corchete, Dalia Quwaider, Elizabeta A. Rojas, Rocío Corral, Ana África Martín, Fernando Escalante, Abelardo Bárez, Juan Luis García, Isidro Sánchez‐García, Ramón García‐Sánz, Jesús F. San Miguel, Norma C. Gutiérrez   +16 more
openalex   +1 more source

Early detection of liver injuries by the Serum enhanced binding test sensitive to albumin post-transcriptional modifications [PDF]

, 2023
Souleiman El Balkhi, Mohamad Ali Rahali, Roy Lakis, François Ludovic Sauvage, Marving Martin, Angelika Janaszkiewicz, Roland Lawson, Ruben Goncalves, Paul Carrier, V. Loustaud‐Ratti, Anne Guyot, Pierre Marquet, Florent Di Meo, Franck Saint‐Marcoux   +13 more
openalex   +1 more source

Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]

, 2016
Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P, Byrne, James A, Chang, Katherine M, Hermann, Kip J, Lee, Patrick C, Lipshutz, Gerald S, Schoenberg, Benjamen E, Truong, Brian, Vega-Crespo, Agustin, Wu, Lily   +9 more
core   +3 more sources

Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation

Nucleic Acids Research, 2019
A complex and highly orchestrated gene expression program chiefly establishes the properties that define the adipocyte phenotype, in which the vast majority of factors are involved in transcriptional regulation.
Tongxing Song, Yang Yang, Hongkui Wei, Xiaowei Xie, Jinxin Lu, Qianhui Zeng, Jie Peng, Yuanfei Zhou, Si-wen Jiang, Jian Peng   +9 more
semanticscholar   +1 more source

PARylation-mediated post-transcriptional modifications in cancer immunity and immunotherapy

Frontiers in Immunology
Poly-ADP-ribosylation (PARylation) is a post-translational modification in which ADP-ribose is added to substrate proteins. PARylation is mediated by a superfamily of ADP-ribosyl transferases known as PARPs and influences a wide range of cellular functions, including genome integrity maintenance, and the regulation of proliferation and differentiation.
Kazuya Matsumoto, Yoshinori Matsumoto, Jun Wada   +2 more
openaire   +3 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Interaction of MaERF11 with the E3 ubiquitin ligase MaRFA1 is involved in the regulation of banana starch degradation during postharvest ripening

Horticultural Plant Journal
Banana fruit ripening is a highly regulatory process involving various layers consisting of transcriptional regulation, epigenetic factor, and post-translational modification.
Mengge Jiang, Yingying Yang, Wei Wei, Chaojie Wu, Wei Shan, Jianfei Kuang, Jianye Chen, Shouxing Wei, Wangjin Lu   +8 more
doaj   +1 more source

Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript Ast in human cells [PDF]

, 2022
Mariana Estevez, Rui Li, Biplab Paul, K. Daneshvar, Alan C. Mullen, Fabio Romerio, Balasubrahmanyam Addepalli   +6 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Subgenome Dominance in Allotetraploid Actinidia valvata Regulates RNA m6A Modification for Waterlogging Tolerance

Advanced Science
Polyploidization is a major driving force for evolutionary innovation and environmental adaptation in plants and is notably prevalent in kiwifruits.
Xiaoli Hu, Changbin Xu, Xiaolan Li, Lin Li, Yu Bao, Miaofeng Gu, Xinyi Li, Liuqing Huo, Jinli Gong, Xiaolong Li, Minhui Wang, Kai Xu, Xueren Yin, Zhangjun Fei, Xuepeng Sun   +14 more
doaj   +1 more source