Results 171 to 180 of about 348,774 (324)

Assessing the impact of non-additive noise on modelling transcriptional regulation with Gaussian processes [PDF]

open access: yes, 2013
In transcriptional regulation, transcription factors (TFs) are often unobservable at mRNA level or may be controlled outside of the system being modelled.
Davies, V., Husmeier, D.
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

GenemiaAfor post‐transcriptional modification of tRNAXXAis important for morphological and metabolic differentiation inStreptomyces [PDF]

open access: bronze, 2019
Oksana Koshla   +10 more
openalex   +1 more source

Additional file 11 of Transcriptome-wide m6A profiling reveals mRNA post-transcriptional modification of boar sperm during cryopreservation

open access: gold, 2021
Ziyue Qin   +8 more
openalex   +2 more sources

Central Dysmyelination in SSADH‐Deficient Humans and Mice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer   +11 more
wiley   +1 more source

Expression of MHC II genes

open access: yes, 2005
Innate and adaptive immunity are connected via antigen processing and presentation (APP), which results in the presentation of antigenic peptides to T cells in the complex with the major histocompatibility (MHC) determinants.
Drozina, G.   +3 more
core   +2 more sources

Practice Recommendations for Genetic Testing of Ataxias

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan   +7 more
wiley   +1 more source

Occurrence of RNA post-transcriptional modifications in plant viruses and viroids and their correlation with structural and functional features

open access: hybrid, 2022
Joan Márquez‐Molins   +4 more
openalex   +1 more source

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