Results 311 to 320 of about 571,207 (361)

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Emerging roles of long non-coding RNAs in osteoarthritis: from molecular mechanisms to therapeutic opportunities. [PDF]

RNA Biol
Zhao Y, Zhang Y, Peng Y, Zheng Z, Li Q, Shen J, Wang H, Liu F.   +7 more
europepmc   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

The Emerging Role of METTL3 in Lung Diseases. [PDF]

Int J Mol Sci
Dong Y, Liu Y, Marciano D, Nefzi A, Black SM, Wang T.   +5 more
europepmc   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

The multifaceted role of post-translational modifications in macrophage polarization: from mechanisms to therapeutic targets. [PDF]

Front Immunol
Guo R, Qi F.
europepmc   +1 more source

From Transcriptome to Therapy: The ncRNA Revolution in Neurodevelopmental Disorders. [PDF]

Brain Sci
Zhao J, Li S, Jin X.
europepmc   +1 more source

Subtype-Specific m⁶A circRNA Methylation Patterns Identify Epigenetic Biomarker Candidates of Potential Diagnostic and Prognostic Significance in Breast Cancer. [PDF]

Int J Mol Sci
Qattan A, Alkhayal W, Suleman K, Al-Tweigeri T, Tulbah A.   +4 more
europepmc   +1 more source

Functional cross-talks between transcription, alternative splicing, translation and novel post-translational modifications in Alzheimer disease: fill missings using proteomics

openalex   +1 more source