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Transcriptome-Wide Identification and Analysis Reveals m⁶A Regulation of Porcine Intestinal Epithelial Cells Under TGEV Infection. [PDF]

Vet Sci
Liu Y, Zhou G, Wang G, Wu Z.
europepmc   +1 more source

Research Status and Latest Progress in the Regulatory Mechanisms of ABCA1. [PDF]

Int J Mol Sci
Chen X, Zhou Y, Yang J, Xue S, Wang Q, Guo X, Zhang Y, Niu W.   +7 more
europepmc   +1 more source

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Small nucleolar RNAs and RNA-guided post-transcriptional modification.

Essays in Biochemistry, 2013
snoRNAs (small nucleolar RNAs) constitute one of the largest and best-studied classes of non-coding RNAs that confer enzymatic specificity. With associated proteins, these snoRNAs form ribonucleoprotein complexes that can direct 2′-O-methylation or pseudouridylation of target non-coding RNAs.
L. Lui, T. Lowe
semanticscholar   +3 more sources

Minimal post-transcriptional modification of yeast mitochondrial ribosomal RNA.

Journal of Molecular Biology, 1975
Yeast mitochondrial ribosomal RNAs (21 S and 15 S) † have been analysed for methylated residues and pseudo-uridine content. Analysis of methyl-3H-labelled nucleosides in 21 S rRNA shows the presence of only two methylated residues with a molar yield of approximately one; they are presumably ribose methylated, because in 32PO4-labelled 21 S RNA two ...
J. Klootwijk, I. Klein, L. Grivell
semanticscholar   +3 more sources

RNA post-transcriptional modification speaks to chromatin

Nature Genetics, 2020
The role of N6-methyladenosine (m6A) is still not fully understood. Two new studies advance understanding of this RNA modification. One shows that m6A modification of nascent messenger RNA promotes transcription by recruiting the histone H3 K9 demethylase KDM3B. Another study identifies genetic variants that affect m6A deposition and human disease.
Dalen Chan, Pedro J. Batista
openaire   +2 more sources

Comprehensive review and assessment of computational methods for predicting RNA post-transcriptional modification sites from RNA sequences

Briefings Bioinform., 2019
RNA post-transcriptional modifications play a crucial role in a myriad of biological processes and cellular functions. To date, more than 160 RNA modifications have been discovered; therefore, accurate identification of RNA-modification sites is ...
Zhen Chen, Pei Zhao, Fuyi Li, Yanan Wang, A. I. Smith, G. I. Webb, T. Akutsu, Abdelkader Baggag, H. Bensmail, Jiangning Song   +9 more
semanticscholar   +1 more source

Cancer cells govern miR‐2909 exosomal recruitment through its 3′‐end post‐transcriptional modification

Cell Biochemistry and Function, 2018
It is widely believed that selective packaging of nucleic acids, especially microRNAs, into exosomes secreted by the cancer cells not only ensures their growth and survival but also helps in the escape from immune surveillance.
Sameena Wani, D. Kaul
semanticscholar   +1 more source