Results 101 to 110 of about 168,624 (246)

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Post-traumatic growth in liver cirrhosis patients: a cross-sectional study on the roles of psychological resilience and fear of progression based on the stress-coping theory

Frontiers in Psychology
ObjectiveTo investigate the current status of post-traumatic growth in patients with liver cirrhosis, analyze the influencing factors of post-traumatic growth, and provide a theoretical basis for the development of targeted intervention measures.MethodsA
Yanyan Wang, Fei Kong, Qing Zhang, Qianqian Wang, Lijuan Yang   +4 more
doaj   +1 more source

The role of attachment in emotion regulation of traumatic stress

, 2011
Recent research has shown that there is a positive relationship between insecure attachment and psychopathology (van IJzendoorn, Bakermans-Kranenburg & Juffer, 2008).
Arikan, Gizem
core  

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Scoping Review of Vicarious Post-Traumatic Growth Among Nurses: Current Knowledge and Research Gaps

Psychology Research and Behavior Management
Yitong Cai,1 Ming Liu,2 Weixiang Luo,3 Jingping Zhang,1 Chaoran Qu4 1Xiangya School of Nursing, Central South University, Changsha, Hunan, People’s Republic of China; 2Evidence-Based Medicine Center, Lanzhou University, Lanzhou, Gansu, People’s Republic ...
Cai Y, Liu M, Luo W, Zhang J, Qu C
doaj  

Relationships between body image, dyadic coping and post-traumatic growth in breast cancer patients: a cross-sectional study

Frontiers in Psychology
BackgroundThe diagnosis and treatment of cancer triggers not only a negative psychological response for the patient, but also a positive psychological outcome.
Yuan Wang, Shan Wang, Ling Tong, Jiaru Zhuang, Yihan Xu, Yibo Wu, Ling Chen   +6 more
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Vicarious post-traumatic growth in Chinese oncology nurses: A cross-sectional study.

PLoS ONE
In the traditional Chinese culture, vicarious trauma poses a significant threat to oncology nurses who are frequently exposed to death and illness. This exposure can undermine both the physical and mental health of these nurses, potentially affecting ...
Jinghan Xu, Dandan Chen, Blandine Lucrece Jongo Fouelefack, Yunxian Zhou   +3 more
doaj   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Understanding the Traumatic Impact of Serious Chronic Illness

European Psychiatry
Introduction The diagnosis of a severe chronic illness represents a deeply impactful traumatic event, frequently giving rise to initial adverse consequences that can manifest as post-traumatic stress.
M. Theodoratou, H. Diamanti
doaj   +1 more source