Results 81 to 90 of about 9,791,095 (282)

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The prevalence of post-traumatic stress disorder among landslide victims [PDF]

, 2018
Malaysia has been prone to both natural and man-made disasters such as droughts, flood, landslides, haze and others. These disasters affect livelihoods, destroy infrastructure, cause food shortages and health problems.
Ahmad, Jamilah, Lateh, Habibah, Mohamad, Nur Afiqah   +2 more
core   +1 more source

Neurocognition in Post-Traumatic Stress Disorder

, 2009
The negative behavioural and emotional symptoms of Post-Traumatic Stress Disorder (PTSD) have been extensively reported in the literature. However, much less is known about the neuropsychological and neurobiological characteristics of the disorder.This ...
Newell, Tracey
core   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Relationship between post-traumatic growth and symptoms of post-traumatic stress disorder a long time after a volcanic disaster [PDF]

, 2020
Background: Mt. Unzen-Fugendake, located in southwestern Japan, began erupting in November 1990. Forty-three people were killed in the 1991 pyroclastic flow. The eruption lasted for 6 years, and approximately 11,000 people, or about 25% of the population,
Morimoto, Yoshiro, Kinoshita, Hirohisa, Ohta, Yasuyuki, Matsuzaka, Yusuke, Ozawa, Hiroki, Nakane, Hideyuki, Honda, Sumihisa   +6 more
core  

A latent profile analysis of post-traumatic growth in spouses of breast cancer patients

Frontiers in Public Health
IntroductionPost-traumatic growth is the positive psychological changes that an individual may undergo after coping with traumatic events. It can help individuals alleviate negative emotions, reduce physical and mental stress, and enhance self-efficacy ...
Xiaocui Duan, Xiumu Yang, Xiumu Yang, Yongli Duan, Zhengfu Shen, Yunbo Xiong, Caixia Sun, Yongxia Chen, Yujiao Shao, Xuejun Xu, Shuang Zhao, Zeyu Zhang, Shiqing Zhang, Yue Yang   +13 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Analisis Koping dan Pertumbuhan Pasca-trauma pada Masyarakat Terpapar Konflik

Psikohumaniora: Jurnal Penelitian Psikologi, 2018
Prolonged conflict in Aceh has caused trauma in people who were directly affected. Aside from post-traumatic disorder, a traumatic event can bring out post-traumatic growth (PTG) too.
Marty Mawarpury
doaj   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source