Results 131 to 140 of about 167,031 (305)
Advanced Science, EarlyView.This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun +14 more
wiley +1 more source
Posttraumatic stress disorder (PTSD) in the armed forces : health economic considerations.
This paper addresses the use of health economics in relation to posttraumatic stress disorder (PTSD) in the Armed Forces, with a view to assessing the feasibility of carrying out future evaluative studies.
Knapp, Martin +2 more
core
Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Advanced Science, EarlyView.Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
BMC PsychiatryObjectives This study aims to quantify the extent to which cognitive emotional regulation and social alienation independently and interactively predict the severity of post-traumatic stress disorder symptoms in patients after radical mastectomy for ...
Yanan Zhou, Yani Zhou, Hui Tan
doaj +1 more source
مجله علوم روانشناختی, 2020 Background: Numerous studies have investigated the experience avoidance, stress, depression and anxiety of veterans. But research comparing empirical avoidance comparisons in veterans with post-traumatic stress disorder with depressive, anxiety, and ...
Mohammad Mehdi Zare +3 more
doaj
An investigation into healthcare staff exposed to workplace violence [PDF]
, 2003 Violence towards healthcare staff is increasingly prevalent in today's NHS. The aim of this thesis was twofold: to establish the current state of research into this problem; and to contribute to the theoretical understanding of one of the common outcomes
Salter, Daniel C
core
TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain
Advanced Science, EarlyView.TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando +2 more
wiley +1 more source
Cognitive factors in NHS staff responses to violence and aggression [PDF]
, 2006 NHS staff frequently experience violence and aggression, and post-traumatic stress disorder (PTSD) is amongst the potential psychological consequences.
Bishop, Emma Rebecca
core
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Advanced Science, EarlyView.Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song +10 more
wiley +1 more source