Results 141 to 150 of about 135,888 (247)

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Post-Burn Quality of Life, Post-Traumatic Stress Disorder (PTSD), and Insomnia: A Six-Month Follow-Up Study [PDF]

Ilias Tsiampouris, Maria Polikandrioti, Ioannis Κoutelekos, Irene E Gamatsi, C Gakis, Panagiota Makrygianni, Ανδριάνα Μαγγίτα, Georgios Vasilopoulos   +7 more
openalex   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

A right hemisphere safety backup at work: Hypotheses for deep hypnosis, post-traumatic stress disorder, and dissociation identity disorder

, 2013
Gordon Burnand
openalex   +1 more source

Structural Covariance Networks in Post-Traumatic Stress Disorder: A Multisite ENIGMA-PGC Study

, 2021
Gopalkumar Rakesh, Mark W. Logue, Emily K. Clarke‐Rubright, Erin N. O’Leary, Courtney C. Haswell, Hong Xie, Paul M. Thompson, Emily L. Dennis, Neda Jahanshad, Saskia B.J. Koch, Jessie L. Frijling, Laura Nawijn, Miranda Olff, Mirjam van Zuiden, Faisal Rashid, Xi Zhu, Michael D. De Bellis, Judith K. Daniels, Anika Sierk, Antje Manthey, Jennifer S. Stevens, Tanja Jovanović, Murray B. Stein, Martha E. Shenton, Steven J.A. van de Werff, Nic J.A. van de Wee, Robert Vermeiren, Christian Schmahl, Julia Herzog, Milissa L. Kaufman, Lauren K. O’Connor, Lauren A. M. Lebois, Justin T. Baker, Staci A. Gruber, Jonathan D. Wolff, Erika J. Wolf, Sherry R. Wintemitz, A. Gönenç, Kerry J. Ressler, David Hofmann, Richard A. Bryant, Mayuresh S. Korgaonkar, Elpiniki Andrew, Li Wang, Ye Zhu, Gen Li, Dan J. Stein, Jonathan Ipser, Sheri‐Michelle Koopowitz, Sven C. Mueller, Anna R. Hudson, Luan Phan, Bobak Hosseini, Kevin Angstadt, Anthony P. King, Marijo Tamburrino, Brynn C. Skilliter, Elbert Geuze, Sanne J.H. van Rooij, Tim Varkevisser, Katie A. McLaughlin, Margaret A. Sheridan, Matthew Peverill, Kelly Sambrook, Dick J. Veltman, Kathleen Thomaes, Scott M. Nelson, Geoffrey May, Lee A. Baugh, Gina L. Forster, Raluca M. Simons, Jeffrey S. Simons, Vincent A. Magnotta, Kelene A. Fercho, Adi Maron‐Katz, Stefan S. du Plessis, Seth G. Disner, Nicholas D. Davenport, Sophia I. Thomopoulos, Benjamin Suarez‐Jimenez, Tor D. Wager, Yuval Neria, Negar Fani, Henrik Walter, Inga K. Koerte, Jessica Bomyea, Kyle Choi, Alan N. Simmons, Elizabeth A. Olson, Isabelle M. Rosso, Thomas Straube, Theo G.M. van Erp, Tian Chen, Andrew S. Cotton, John T. Wall, Richard J. Davidson, Terri A. deRoon‐Cassini, Jacklynn M. Fitzgerald, Christine L. Larson, Evan M. Gordon   +99 more
openalex   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Biomarkers and Mechanisms of Cardiovascular Susceptibility and Resilience to Post-Traumatic Stress Disorder. [PDF]

Rev Cardiovasc Med
B Manukhina E, K Mallet M, E Tseilikman V, V Kondashevskaya M, P Budanova O, Fred Downey H, T Mallet R.   +6 more
europepmc   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Pharmacological Management of Post-Traumatic Stress Disorder; A Qualitative Analysis of ClinicalTrials.gov. [PDF]

Drug Des Devel Ther
Alorfi NM.
europepmc   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source