Results 71 to 80 of about 363,545 (300)

MXene/PEDOT Functional Coatings on Flexible Microelectrode Arrays for Multianalyte In Vivo Neurochemical Sensing and Electrophysiology

Advanced Functional Materials, EarlyView.
A MXene/PEDOT coating enables multimodal functionality and dual‐analyte detection of dopamine and serotonin in flexible microelectrode arrays while enhancing electrophysiological recording quality. The anti‐fouling, low‐impedance interface overcomes key limitations of conventional coatings, providing a robust and versatile platform to investigate the ...
Ilaria Gatti, Karamullah Eisawi, Umisha Siwakoti, Greyson Jadwin, Ashmita Sigdel, Michela Chiappalone, Deepak Kumbhare, Michael Naguib, Elisa Castagnola   +8 more
wiley   +1 more source

Sex-based differences in brain morphometry under chronic stress: A pilot MRI study

Heliyon
Background: Sex-based differences are known to be a significant feature of chronic stress; however, the morphological mechanisms of the brain underlying these differences remain unclear. The present study aimed to use magnetic resonance imaging (MRI) and
Zhilei Shang, Nianqi Liu, Hui Ouyang, Xiaojie Cai, Wenjie Yan, Jing Wang, Jingye Zhan, Yanpu Jia, Chenqi Xing, Lijun Huang, Lili Wu, Weizhi Liu   +11 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder

Frontiers in Genetics
Background: Alcohol use disorder (AUD) is a complex condition associated with adverse health consequences that affect millions of individuals worldwide.
Diego E. Andrade-Brito, Diego E. Andrade-Brito, Diana L. Núñez-Ríos, Diana L. Núñez-Ríos, José Jaime Martínez-Magaña, José Jaime Martínez-Magaña, Sheila T. Nagamatsu, Sheila T. Nagamatsu, Gregory Rompala, Lea Zillich, Stephanie H. Witt, Shaunna L. Clark, Maria C. Lattig, Janitza L. Montalvo-Ortiz, Janitza L. Montalvo-Ortiz   +14 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Survivors of avalanche accidents: posttraumatic stress disorder symptoms and quality of life: a multicentre study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background As any traumatic event, avalanches could trigger psychological disorders on survivors. Our objectives were to determine the prevalence of post-traumatic stress disorder among avalanche survivors and to evaluate post-traumatic stress disorder ...
Charlotte Léonard, Anaëlle Charriau-Perret, Guillaume Debaty, Loïc Belle, Cécile Ricard, Caroline Sanchez, Pierre-Marie Dupré, Gregory Panoff, Thierry Bougerol, Damien Viglino, Marc Blancher, the Northern French-Alps Emergency Network (“RENAU”)   +11 more
doaj   +1 more source

Serving Those Who Served Us First: Evidence to Support Effective Interventions for Returning Veterans [PDF]

, 2014
Objectives of Presentation: Discuss the impact of traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) on occupational performance Identify a minimum of 3 interventions in the scope of occupational therapy that are effective in ...
Barretto, Tracey, Fiocco, Kelly, Tavares, Dana   +2 more
core   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Post-traumatic amnesia and the nature of post-traumatic stress disorder after mild traumatic brain injury [PDF]

, 2009
The prevalence and nature of post-traumatic stress disorder (PTSD) following mild traumatic brain injury (MTBI) is controversial because of the apparent paradox of suffering PTSD with impaired memory for the traumatic event. In this study, 1167 survivors
Bryant, Richard, Clark, Christopher Richard, Creamer, Mark, McFarlane, Alexander C, O'Donnell, Meaghan, Silove, Derrick   +5 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source