Results 81 to 90 of about 8,428,885 (297)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Aplikasi eye moving desensitization dan reprocessing dalam konseling post-traumatic stress disorder

Teraputik: Jurnal Bimbingan dan Konseling, 2020
Recently more events can appear traumatic effect even if it not treated, it will be post-traumatic stress disorder. Therefore, need the efforts to treat this problem. One of the way is using eye moving desensitization and reprocessing.
Hengki Satrianta
doaj   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Sex-based differences in brain morphometry under chronic stress: A pilot MRI study

Heliyon
Background: Sex-based differences are known to be a significant feature of chronic stress; however, the morphological mechanisms of the brain underlying these differences remain unclear. The present study aimed to use magnetic resonance imaging (MRI) and
Zhilei Shang, Nianqi Liu, Hui Ouyang, Xiaojie Cai, Wenjie Yan, Jing Wang, Jingye Zhan, Yanpu Jia, Chenqi Xing, Lijun Huang, Lili Wu, Weizhi Liu   +11 more
doaj   +1 more source

Neuroendocrinology of Post-Traumatic Stress Disorder

, 2010
Dysregulation of the stress system, including the hypothalamic-pituitary-adrenal (HPA) axis and the locus caeruleus/norepinephrine-sympathetic nervous system (SNS), is involved in the pathophysiology of post-traumatic stress disorder (PTSD), an anxiety disorder that develops after exposure to traumatic life events. Neuroendocrine studies in individuals
Pervanidou, Panagiota, Chrousos, George P.   +1 more
openaire   +3 more sources

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

MicroRNAs in Post-traumatic Stress Disorder

, 2017
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop following exposure to or witnessing of a (potentially) threatening event. A critical issue is to pinpoint the (neuro)biological mechanisms underlying the susceptibility to stress-related disorder such as PTSD, which develops in the minority of ~15% of individuals exposed ...
Snijders, Clara, de Nijs, Laurence, Baker, Dewleen G., Hauger, Richard L., van den Hove, Daniel, Kenis, Gunter, Nievergelt, Caroline M., Boks, Marco P., Vermetten, Eric, Gage, Fred H., Rutten, Bart P. F.   +10 more
openaire   +2 more sources

Evaluation of Post-Traumatic Stress Disorders [PDF]

Military Medicine, 2001
This paper introduces important considerations in the evaluation of psychological reactions to traumatic events. Proper assessment should include consideration of psychometric, cultural, and ethical issues. Mental disorders frequently observed in the aftermath of trauma (acute stress disorder and post-traumatic stress disorder) and stress (adjustment ...
openaire   +2 more sources

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder

Frontiers in Genetics
Background: Alcohol use disorder (AUD) is a complex condition associated with adverse health consequences that affect millions of individuals worldwide.
Diego E. Andrade-Brito, Diego E. Andrade-Brito, Diana L. Núñez-Ríos, Diana L. Núñez-Ríos, José Jaime Martínez-Magaña, José Jaime Martínez-Magaña, Sheila T. Nagamatsu, Sheila T. Nagamatsu, Gregory Rompala, Lea Zillich, Stephanie H. Witt, Shaunna L. Clark, Maria C. Lattig, Janitza L. Montalvo-Ortiz, Janitza L. Montalvo-Ortiz   +14 more
doaj   +1 more source