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A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist

Clinical Reviews in Allergy & Immunology, 2021
Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for a minority of patients, accompanying non-specific symptoms can persist for months following completion of therapy.
Katelyn H. Wong   +2 more
openaire   +2 more sources

Lyme disease and post-treatment Lyme disease syndrome: the neglected disease in our own backyard

Public Health, 2014
A survey was developed to assess experience and opinions about Lyme disease and post-treatment Lyme disease syndrome (PTLDS) among faculties in public health. No previous surveys of public health faculties have been found in the literature.This is a cross sectional study of public health school faculty members designed to measure knowledge and ...
L A, Crowder   +4 more
openaire   +2 more sources

Audiologic Manifestations of Patients with Post-Treatment Lyme Disease Syndrome

Ear & Hearing, 2003
The purpose of this study was to characterize auditory function in patients diagnosed with post-treatment Lyme disease syndrome (PTLDS).Eighteen patients with PTLDS were evaluated and compared to a normal population. Evaluations consisted of pure tone and speech thresholds, word recognition (WRS), acoustic immittance battery, auditory brain stem ...
Lawrence I, Shotland   +7 more
openaire   +2 more sources

Characterizing Post-treatment Lyme Disease Syndrome: A Mixed Methods Study of Patients at a Lyme Disease Clinic in Rhode Island.

Rhode Island medical journal (2013), 2021
Mixed quantitative and qualitative research methods may be useful for characterizing the experiences of patients with post-treatment Lyme disease syndrome.15 participants completed demographic and screening questions, surveys assessing quality of life, fatigue, pain, cognitive functioning, and other patient- reported outcomes, a semi-structured in ...
Sara E, Vargas   +7 more
openaire   +2 more sources

Single-cell sequencing of PBMC characterizes a distinct inflammatory monocyte subset in Lyme disease patients with Post-Treatment Lyme Disease Syndrome (PTLD)

The Journal of Immunology, 2023
Abstract Lyme disease (LD) is the most common tick-borne disease in the United States. Most LD patients can return to healthy (RTH) status after antibiotic treatment. Still, 20% of LD patients develop Post-Treatment Lyme Disease Syndrome (PTLD), including fatigue and musculoskeletal pain that persist for a long time.
Xin Chen   +8 more
openaire   +1 more source

FLAIR and magnetization transfer imaging of patients with post-treatment Lyme disease syndrome

Neurology, 2001
To determine patterns of abnormalities on cerebral MRI that may characterize subgroups of patients with post-treatment Lyme disease syndrome (PTLDS) and to help identify pathomechanisms of disease.The authors analyzed the distribution of cerebral lesions in a cohort of 27 patients with PTLDS.
K, Morgen   +6 more
openaire   +2 more sources

Aktuelle integrative und supportive Therapieoptionen bei Post-Treatment Lyme Disease Syndrome (PTLDS) und Chronischer Lyme-Disease (CLD)

Zeitschrift für Orthomolekulare Medizin
ZusammenfassungBei der Lyme-Borreliose übertragen Zecken die Krankheitserreger von infizierten Tieren auf den Menschen. Von der Spätmanifestation der Infektion, auch als „Chronische Lyme-Borreliose“ (CLD) bezeichnet, ist das „Posttherapeutische Lyme-Borreliose-Syndrom“ (PTLDS ...
Michael Kramer   +3 more
openaire   +2 more sources

A distinct autoimmune signature in Post-treatment Lyme Disease Syndrome (PTLD)

The Journal of Immunology
Abstract Post-Treatment Lyme Disease (PTLD) is characterized as a persistent inflammatory condition in a large fraction of patients following antibiotic treatment for Borreliella infection, but what leads to PTLD is not known. Here, we analyzed 56 peripheral blood mononuclear cell (PBMC) samples from 23 individuals at risk for PTLD in a ...
Xin Chen   +10 more
openaire   +1 more source

The Use of Dapsone as a Novel “Persister” Drug in the Treatment of Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome

Journal of Clinical and Experimental Dermatology Research, 2016
Dapsone (diaminodiphenyl sulfone, i.e., DDS) is commonly used to treat dermatological conditions including acne, dermatitis herpetiformis, and leprosy. Mycobacterium leprae, a known "persister" bacteria, requires long-term treatment with intracellular medications including rifampin and Dapsone.
openaire   +1 more source

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