Results 61 to 70 of about 6,751 (146)

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Diagnosis, Clinical Manifestations and Treatment of Lyme Disease

Quality in Sport
Introduction and purpose Lyme disease was identified in the 1970s. It is an anthropozoonosis caused by spirochetes from the Borrelia family. This disease is the most common one caused by pathogens transmitted by ticks.
Katarzyna Jakubowska, Aleksandra Janocha, Aneta Jerzak, Paweł Ziemba   +3 more
doaj   +1 more source

Prevalence and determinants of persistent symptoms after treatment for Lyme borreliosis: study protocol for an observational, prospective cohort study (LymeProspect)

BMC Infectious Diseases, 2019
Background After antibiotic treatment of Lyme borreliosis, a subset of patients report persistent symptoms, also referred to as post-treatment Lyme disease syndrome.
Hedwig D. Vrijmoeth, Jeanine Ursinus, Margriet G. Harms, Tizza P. Zomer, Stefanie A. Gauw, Anna D. Tulen, Kristin Kremer, Hein Sprong, Hans Knoop, Yolande M. Vermeeren, Barend van Kooten, Leo A. B. Joosten, Bart-Jan Kullberg, Joppe W. R. Hovius, Cees C. van den Wijngaard   +14 more
doaj   +1 more source

Climate change effects in older people's health: A scoping review

Journal of Advanced Nursing, Volume 81, Issue 12, Page 8066-8079, December 2025.
Abstract Background Climate change has serious consequences for the morbidity and mortality of older adults. Objective To identify the effects of climate change on older people's health. Methods A scoping review was conducted following the Joanna Briggs Institute guidelines and the PRISMA‐ScR checklist.
Eva Mª Montoro‐Ramírez, Laura Parra‐Anguita, Carmen Álvarez‐Nieto, Gema Parra, Isabel Mª López‐Medina   +4 more
wiley   +1 more source

Lyme disease: case report of persistent Lyme disease from Pulaski County, Virginia

International Medical Case Reports Journal, 2013
James R Palmieri,1 Scott King,1 Matthew Case,1 Arben Santo21Department of Microbiology, Infectious and Emerging Diseases, 2Department of Pathology, Edward Via College of Osteopathic Medicine, Blacksburg, VA, USAAbstract: A 50-year-old woman from Pulaski,
Palmieri JR, King S, Case M, Santo A
doaj  

Biomarker-Based Analysis of Pain in Patients with Tick-Borne Infections before and after Antibiotic Treatment

Antibiotics
Tick-borne illnesses (TBIs), especially those caused by Borrelia, are increasingly prevalent worldwide. These diseases progress through stages of initial localization, early spread, and late dissemination.
Kunal Garg, Abbie Thoma, Gordana Avramovic, Leona Gilbert, Marc Shawky, Minha Rajput Ray, John Shearer Lambert   +6 more
doaj   +1 more source

“Repurposing” Disulfiram in the Treatment of Lyme Disease and Babesiosis: Retrospective Review of First 3 Years’ Experience in One Medical Practice

Antibiotics, 2020
A total of 71 patients with Lyme disease were identified for analysis in whom treatment with disulfiram was initiated between 15 March 2017 and 15 March 2020. Four patients were lost to follow-up, leaving 67 evaluable patients.
Jiachen Gao, Zhaodi Gong, Dawn Montesano, Erica Glazer, Kenneth Liegner   +4 more
doaj   +1 more source

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

MedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li, Junli Li, Jiazheng Wei, Weixin Du, Cheng Su, Xiaobin Shen, Aihua Zhao, Miao Xu   +7 more
wiley   +1 more source

Complement Evasion in Borrelia spirochetes: Mechanisms and Opportunities for Intervention

Antibiotics, 2019
Lyme disease (LD) is an increasingly prevalent, climate change-accelerated, vector-borne infectious disease with significant morbidity and cost in a proportion of patients who experience ongoing symptoms after antibiotic treatment, a condition known as ...
Jonathan W. Locke
doaj   +1 more source

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Annals of Clinical and Translational Neurology, Volume 12, Issue 9, Page 1785-1793, September 2025.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay   +11 more
wiley   +1 more source