Results 41 to 50 of about 4,019 (310)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Kinetic characteristics investigation of the Yingxingping rockslide based on discrete element method combined with discrete fracture network [PDF]
Natural Hazards and Earth System SciencesThe development of rock fractures on the mountain ridge in meizoseismal area may lead to fatal rockslides. This study focused on a catastrophic post-earthquake rockslide case in Wenchuan, Southwestern China.
B. Liu +11 more
doaj +1 more source
Working with broken agents: Exploring computational 2D morphometrics for studying the (post)depositional history of potsherds [PDF]
, 2019 The study of size and shape of ceramic fragments is a common approach used for unraveling the depositional and post-depositional history of archaeological assemblages.
Astaloş, C +4 more
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Stirred remanent magnetization: a laboratory analogue of post-depositional realignment [PDF]
, 1980 The remanent magnetization acquired by a slurry stirred in a magnetic field was measured as a function of the applied field, stirring rate and water content.
Tucker, P.
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Technology and taphonomy of the Middle Paleolithic assemblage from the Uzun Mera site in Macedonia
Quaternary Environments and HumansThe open-air site of Uzun Mera in eastern North Macedonia provides new insights into Middle Paleolithic Neanderthal behaviour and site formation processes in the understudied Balkan Peninsula.
Darko Stojanovski +5 more
doaj +1 more source
Post-depositional reactivity of the plutonium in different sediment facies from the English Channel - an experimental approach [PDF]
, 2005 The post-depositional reactivity of the plutonium was investigated in bottom sediments collected in the central English Channel using an experimental approach.
M. Rozet +5 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Frontiers in Earth Science, 2015 Super-eruptions generating hundreds of cubic kilometres of pyroclastic density currents are commonly recorded by thick, welded and lava-like ignimbrites.
Yan eLavallée +11 more
doaj +1 more source