Results 61 to 70 of about 4,019 (310)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Book Review: Archaeological and Anthropological Sciences by L. Shillito, E. Fairnell and H. S. Williams (eds)

open access: yesEXARC Journal, 2014
A set of eleven articles resulting from the call for papers for the Sixth UK Experimental Archaeology Conference (held in York in January 2012) is now published in a special issue of the Journal of Archaeological and Anthropological Sciences.
Katy Whitaker
doaj  

The landslide problem

open access: yesJournal of Palaeogeography, 2015
The synonymous use of the general term “landslide”, with a built-in reference to a sliding motion, for all varieties of mass-transport deposits (MTD), which include slides, slumps, debrites, topples, creeps, debris avalanches etc.
G. Shanmugam
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Book Review: Forensic Archaeology: the Application of Comparative Excavation Methods and Recording Systems by Laura Evis

open access: yesEXARC Journal, 2017
This book is a rewrite of Evis’ PhD thesis compiled between October 2010 and March 2014 at Bournemouth University (University of Exeter 2017). The study was an evaluation of the archaeological excavation methods and recording systems used in the United ...
Ceilidh Lerwick
doaj  

A magnetization process of sediments: laboratory experiments on post-depositional remanent magnetization [PDF]

open access: yesGeophysical Journal International, 1981
Summary. Palaeomagnetic studies require a theory of magnetization mechanism of sediments and a method of estimating magnetic field intensity from their remanences. This paper establishes a physical basis for the generation of the remanence in deep-sea and lake sediments experimentally.
Y.-i. Otofuji, S. Sasajima
openaire   +1 more source

Sistema deposicional e petrografia dos conglomerados e arenitos da borda sul da Bacia do Itajaí, localidade de Gaspar, Santa Catarina [PDF]

open access: yes, 2014
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Filosofia e Ciências Humanas. Geologia.O preenchimento sedimentar em bacias de foreland é controlado principalmente por fatores tectônicos, que governam o aporte sedimentar e o espaço de ...
Lopes, Juliana Aparecida Gonçalves
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Application of sequence stratigraphic concepts to the cretaceous Urgonian carbonate platform, southeast France [PDF]

open access: yes, 1992
Carbonate platforms are increasingly being studied using sequence stratigraphic concepts and models borrowed from the study of siliciclastic shelves in passive margin settings. The direct transposition of the stratigraphic model for a siliciclastic shelf
Hunt, David William
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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