Results 71 to 80 of about 4,019 (310)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Towards successful OSL sampling strategies in glacial environments : deciphering the influence of depositional processes on bleaching of modern glacial sediments from Jostedalen, Southern Norway [PDF]

, 2014
GEK was supported by NERC studentship F008589/1 and was a SAGES affiliated student. Financial support in the form of a New Workers Research Award is acknowledged from the QRA.
King, Georgina E., Robinson, Ruth Alison Joyce, Finch, Adrian Anthony, Robinson, R.A.J., King, G.E., Finch, A.A.   +5 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Carboniferous basement rocks of northern Britain [PDF]

, 1987
The study of Carboniferous basement rocks of northern Britain has concentrated on the dominantly clastic rock succession which unconformably overlies the Lower Palaeozoic basement and occurs beneath the lowermost Carboniferous limestones in areas ...
Kimber, R.N, Kimber, Roger Neil
core  

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Biomolecules in Pleistocene fossils from tropical cave indicate fossil biofilm

Scientific Reports
Finding biomolecules in fossils is a challenging task due to their degradation over time from physical, chemical, and biological factors. The primary hypothesis for explaining the presence of biomolecules in fossilized bones tissues suggests their ...
Daniel Vieira de Sousa, Paulo Victor Sciammarella Maia, Estevan Eltink, Luciano de Moura Guimarães   +3 more
doaj   +1 more source

Understanding the burden of orofacial involvement and patient treatment preferences in systemic sclerosis: results from a large international survey

Arthritis Care &Research, Accepted Article.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc), yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprising 38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

A new OSL dose model to account for post-depositional mixing of sediments [PDF]

In applications of optically stimulated luminescence (OSL) dating to unconsolidated sediments, the burial age of a sample of grains is estimated using statistical models of the distribution of the experimentally determined equivalent doses of the grains,
Zenobia Jacobs (435157), Richard G Roberts (16073741), Luke A Yates (20271897), Bruno David (441047), Barry W Brook (13461825), Bo Li (112195), Zach Aandahl (16474749)   +6 more
core   +4 more sources

Pool-fills: a window to palaeoflood history and response in bedrock-confined rivers [PDF]

, 2004
Channel-scale sedimentary units associated with bedrock-controlled riffle-pool morphology are examined in detail along Sandy Creek gorge, an ephemeral stream in arid south-eastern central Australia.
Brierley, G.J., Jansen, J.D.
core   +1 more source

Laser Powder Bed Fusion of Alumina: Effects of Scanning Strategies on External and Internal Defects

Advanced Engineering Materials, EarlyView.
This study investigates how scanning strategies affect pure alumina in laser powder bed fusion. Linear 45° scanning yields uniform surfaces but high porosity, while the island‐concentric strategy provides higher density with through‐holes favorable for infiltration. Findings highlight pathways toward optimizing defect‐free alumina parts.
Mohamed Abdelmoula, Gökhan Küçüktürk, Duran Kaya, David Grossin, Christophe Tenailleau, Benjamin Duployer, Enrique Juste, Fabrice Petit   +7 more
wiley   +1 more source