Results 61 to 70 of about 614,163 (313)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Effect of coloured shade nets on yield and quality of pomegranate (Punica granatum) cv. Mridula in semi-arid region of Punjab

The Indian Journal of Agricultural Sciences, 2016
The productivity of pomegranate (Punica granatum L.) cv. Mridula was examined under shade nets of different colours (Red, Black and Green) with shade intensities (Red 50% PAR, Black 50% PAR, Green 35% PAR and 50% PAR) in Abohar, Punjab over two growing ...
V S MEENA, POONAM KASHYAP, D D NANGARE, J SINGH   +3 more
doaj   +1 more source

Forecasting Crop Basis Using Historical Averages Supplemented with Current Market Information [PDF]

This research compares practical methods of forecasting basis, using current market information for wheat, soybeans, corn, and milo (grain sorghum) in Kansas.
Dhuyvetter, Kevin C., Kastens, Terry L., Taylor, Mykel R.   +2 more
core   +1 more source

Post-harvest sown catch crops – results from two years of organic field trials [PDF]

, 2013
Post-harvest sown catch crops should be sown as early as possible in order to obtain maximum biomass and nutrient uptake in the harvested crop, as biomass production decreased by 2-3.5 percent per day, when time of sowing was postponed throughout August.
Askegaard, M., Bertelsen, I., Madsen, H.K.   +2 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Green solvent extraction of health boosting phenolics from pigeon pea husk

Scientific Reports
The optimization of phenolic compound extraction from pigeon pea (Cajanus cajan L.) husk was explored by manipulating three key process variables: aqueous ethanol concentration (20–60% v/v), extraction temperature (30–60 °C), and extraction time (2–6 h).
Deepika Goswami, Manju Bala, D. Mridula, Rajesh Kumar Vishwakarma, P. N. Guru   +4 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Machine-Learning-Based Prediction Model for Total Glycoalkaloid Accumulation in Yukon Gold Potatoes

Foods
Potatoes are the most extensively cultivated vegetable crop in Canada and rank as the fifth largest primary agricultural commodity. Given their diverse end uses and significant market value, particularly in processed forms, ensuring consistent quality ...
Saipriya Ramalingam, Diksha Singla, Mainak Pal Chowdhury, Michele Konschuh, Chandra Bhan Singh   +4 more
doaj   +1 more source

A laboratory method to evaluate the sensitivity of Colletotrichum musea to post harvest fungicides [PDF]

, 2008
Introduction. Ce protocole vise à détecter et évaluer des variations de sensibilité dans des populations de Colletotrichum musae vis-à-vis des fongicides actuellement utilisés pour le contrôle des maladies de conservation des bananes.
Chilin-Charles, Yolande, De Lapeyre de Bellaire, Luc   +1 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source