Results 111 to 120 of about 6,758,662 (333)
Prerequisites for Affective Signal Processing (ASP) - Part V: A response to comments and suggestions [PDF]
, 2011 In four papers, a set of eleven prerequisites for affective signal processing (ASP) were identified (van den Broek et al., 2010): validation, triangulation, a physiology-driven approach, contributions of the signal processing community, identification of
Broek, Egon L. van den +4 more
core +1 more source
Ophthalmology (Rochester, Minn.), 2020 OBJECTIVE An independent Safety Review Committee (SRC; supported by Novartis Pharma AG [Basel, Switzerland]) analyzed investigator-reported cases of intraocular inflammation (IOI), endophthalmitis and retinal arterial occlusion in the phase 3 HAWK and ...
J. Monés +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Post hoc verification of quantum computation
, 2015 With recent progress on experimental quantum information processing, an important question has arisen as to whether it is possible to verify arbitrary computation performed on a quantum processor.
Fitzsimons, Joseph F., Hajdušek, Michal
core
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Post Hoc Subgroup Analysis and Identification—Learning More from Existing Data
ProceedingsPersonalized nutrition aims to exploit heterogeneity. One reason for heterogeneity may be the presence of one or more subgroups that respond better to a dietary intervention than the observed average in the entire population considered.
Elizabeth Mannion +2 more
doaj +1 more source
Securitization and Post-Crisis Financial Regulation [PDF]
, 2016 There are few types of securities as internationally traded as those issued in securitization (also spelled securitisation) transactions. The post-financial crisis regulatory responses to securitization in the United States and Europe are, at least in ...
Schwarcz, Steven L.
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
, 2009 The transmission capacity of an ad-hoc network is the maximum density of active transmitters per unit area, given an outage constraint at each receiver for a fixed rate of transmission. Assuming that the transmitter locations are distributed as a Poisson
Heath Jr, Robert W., Vaze, Rahul
core +1 more source