Results 81 to 90 of about 6,758,662 (333)

Effect of patient characteristics on the efficacy and safety of imeglimin monotherapy in Japanese patients with type 2 diabetes mellitus: A post‐hoc analysis of two randomized, placebo‐controlled trials

open access: yesJournal of Diabetes Investigation, 2023
Aims/Introduction Substantial variability in demographic and clinical characteristics exists among patients with type 2 diabetes mellitus, which may impact treatment.
Katsuhiko Hagi   +4 more
doaj   +1 more source

Post-hoc power analysis: a conceptually valid approach for power based on observed study data

open access: yesGeneral Psychiatry, 2022
Power analysis is a key component of planning prospective studies such as clinical trials. However, some journals in biomedical and psychosocial sciences request power analysis for data already collected and analysed before accepting manuscripts for ...
N. Quach   +6 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Post hoc Correction of Chromatic Aberrations in Large-Scale Volumetric Images in Confocal Microscopy

open access: yesFrontiers in Neuroanatomy, 2021
Over the last decade, tissue-clearing techniques have expanded the scale of volumetric fluorescence imaging of the brain, allowing for the comprehensive analysis of neuronal circuits at a millimeter scale.
Marcus N. Leiwe   +2 more
doaj   +1 more source

Antagonist conditioning contractions impair agonist functioning [PDF]

open access: yes, 2010
This study assessed the effect of antagonist conditioning contractions (ACC) on the subsequent force and electromyography of an agonist. Twelve subjects performed isokinetic elbow flexion on a dynamometer in 4 test conditions including a baseline ...
Ebben, William   +8 more
core   +2 more sources

Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: A post-hoc study. [PDF]

open access: yes, 2017
Brivaracetam (BRV), a selective, high-affinity ligand for synaptic vesicle protein 2A, is a new antiepileptic drug (AED) for adjunctive treatment of focal (partial-onset) seizures in adults with epilepsy.
Asadi-Pooya, Ali A.   +7 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Fisher's exact approach for post hoc analysis of a chi-squared test.

open access: yesPLoS ONE, 2017
This research is motivated by one of our survey studies to assess the potential influence of introducing zebra mussels to the Lake Mead National Recreation Area, Nevada.
Guogen Shan, Shawn Gerstenberger
doaj   +1 more source

Open plan and academe: pre- and post-hoc conversations [PDF]

open access: yes, 2008
There now exists a strong body of evidence that creative workplaces can, in certain circumstances, exert beneficial influences on organisational cultures and outputs. Academia tends to resist such spaces and faculty buildings.
Fortune, J., Price, I.
core  

E-QED: Electrical Bug Localization During Post-Silicon Validation Enabled by Quick Error Detection and Formal Methods

open access: yes, 2017
During post-silicon validation, manufactured integrated circuits are extensively tested in actual system environments to detect design bugs. Bug localization involves identification of a bug trace (a sequence of inputs that activates and detects the bug)
B Vermeulen   +12 more
core   +1 more source

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