New insights into the pathophysiology of post-stroke spasticity [PDF]
Frontiers in Human Neuroscience, 2015 Spasticity is one of many consequences after stroke. It is characterized by a velocity-dependent increase in resistance during passive stretch, resulting from hyperexcitability of the stretch reflex. The underlying mechanism of the hyperexcitable stretch
Sheng eLi, Gerard eFrancisco
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Early brain imaging predictors of post-stroke spasticity
Journal of Rehabilitation Medicine, 2021 Background: Post-stroke spasticity is a major factor disturbing rehabilitation and functional recovery in stroke survivors. Clinical predictors of post-stroke spasticity have often been discussed, but brain image predictors for spasticity have been ...
Songjin Ri +2 more
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BoNT-A for Post-Stroke Spasticity: Guidance on Unmet Clinical Needs from a Delphi Panel Approach
Toxins, 2021 There is extensive literature supporting the efficacy of botulinum toxin (BoNT-A) for the treatment of post-stroke spasticity, however, there remain gaps in the routine management of patients with post-stroke spasticity. A panel of 21 Italian experts was
Alessio Baricich +7 more
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Neurophysiological Changes in Post Stroke Spasticity Patients
The Iraqi Journal of Medical Sciences, 2023 Background: A stroke is a serious life-threatening medical condition that occurs when the blood supply to part of the brain is disrupted. Spasticity is a state, in which, there is an increase in muscle tone or stiffness, which might be associated with ...
Safa M. Fawzi +3 more
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Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review [PDF]
Annals of MedicineBackground Stroke is a leading cause of long-term disability and death worldwide. Spasticity after stroke seriously affects patients’ quality of life.
Qianwen Xu +4 more
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Does the Diffusion Profile Differ Between Botulinum Toxin Type a Formulations? Implications for the Management of Post-Stroke Spasticity [PDF]
ToxinsBotulinum toxin type A is a first-line treatment for post-stroke spasticity, with selective action at nerve endings and minimal effects beyond the injection site.
Alessandro Picelli +4 more
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Superior efficacy of 100-Hz transcutaneous electrical nerve stimulation in reducing post-stroke spasticity: a systematic review and meta-analysis [PDF]
Journal of NeuroEngineering and RehabilitationBackground Post-stroke spasticity is a prevalent complication of upper motor neuron injury, hindering motor recovery, independence, and quality of life.
Yingxiu Diao +6 more
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Long-Term Management of Post-Stroke Spasticity with Botulinum Toxin: A Retrospective Study [PDF]
ToxinsStroke-induced spasticity is a prevalent condition affecting stroke survivors, significantly impacting their quality of life. Botulinum Toxin A injections are widely used for its management, yet the long-term effects and optimal management strategies ...
Nicoletta Falcone +3 more
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, 2021 Spasticity is a common complication of stroke that results in impairments and limitations in performance of activities and participation. Although it is an important problem, spasticity, defined as velocity-dependent muscle overactivity, is only one component of the upper motor neuron syndrome (UMNS).
Gerard E. Francisco +3 more
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Journal of Rehabilitation Medicine, 2023 Background: Real-world data regarding the impact of onabotulinumtoxinA on healthcare resource utilization and costs for post-stroke spasticity are scarce. Objective: To compare differences in 12-month healthcare resource utilization and costs before and
Alberto Esquenazi +6 more
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