Results 51 to 60 of about 5,492,944 (200)
Functional profiling of STXBP1 missense variants using a novel dual‐readout fluorometric assay
Epilepsia, EarlyView.Abstract Objective STXBP1‐related disorders (STXBP1‐RD) are among the most common genetic neurodevelopmental disorders, marked by early onset epilepsy, global developmental delay, and motor impairments. Many missense variants remain uncharacterized, limiting accurate variant interpretation and hindering development of precision therapies.
Elisa A. Waxman +11 more
wiley +1 more source
Analysis of MEP parameters in patients with post stroke spasticity in relation with rTMS therapy
Acta Neurologica BelgicaSpasticity is a common complication of stroke limiting patient’s daily activities. Transcranial magnetic stimulation is a painless and non-invasive method that can potentially reduce post-stroke spasticity (PSS).
Yuvraj Lahre +4 more
semanticscholar +1 more source
The Onset and Frequency of Spasticity After First Ever Stroke
, 2018 Spasticity is one of the most important causes of disability after stroke. In spite of high incidence of spasticity, little is known about the relationship between the occurrence and the development of spasticity.
Zoghi, Maryam +7 more
core +1 more source
Advanced quantitative estimation methods for spasticity: a literature review
Journal of International Medical Research, 2020 Post-stroke spasticity seriously affects patients’ quality of life. Spasticity is considered to involve both neural and non-neural factors. Current clinical scales, such as the Modified Ashworth Scale and the Modified Tardieu Scale, lack reliability and ...
Zichong Luo +4 more
doaj +1 more source
Ibrain, EarlyView.This expert consensus proposes a patient‐centered pathway for functional reconstruction after post‐stroke spastic hemiplegia: “patient goal–pathophysiologic component–treatment target–functional reassessment.” Treatment selection and sequencing across motor retraining, brain–computer interfaces, peripheral nerve surgery, and tendon/soft‐tissue ...
Peng Wen +39 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño +6 more
wiley +1 more source
The early use of botulinum toxin in post-stroke spasticity: study protocol for a randomised controlled trial [PDF]
, 2014 BACKGROUND: Patients surviving stroke but who have significant impairment of function in the affected arm are at more risk of developing pain, stiffness and contractures. The abnormal muscle activity, associated with post-stroke spasticity, is thought to
core +1 more source
Which brain lesions produce spasticity? An observational study on 45 stroke patients.
PLoS ONE, 2019 Spasticity is an important barrier that can hinder the restoration of function in stroke patients. Although several studies have attempted to elucidate the relationship between brain lesions and spasticity, the effects of specific brain lesions on the ...
Kyoung Bo Lee +8 more
doaj +1 more source
Frontiers in Neurology, 2022 Objective This systematic review and meta-analysis aimed to comprehensively evaluate the effectiveness and safety of acupuncture for post-stroke spasticity.
Chen Xue +12 more
semanticscholar +1 more source
PM&R, EarlyView.Abstract Introduction/Objective Diagnostic nerve blocks (DNBs) involve the injection of anesthetic around peripheral nerves to temporarily reduce motor tone. Although they are used clinically to inform spasticity treatment with neurotomy and chemodenervation, there is little research exploring the predictive nature of DNBs.
Katherine Archibold +3 more
wiley +1 more source