Results 181 to 190 of about 656,203 (309)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Mark Poster Letter to Manfred Frank, April 24, 1988

open access: yes
Original file path: CTI_emails\CT-1988\FRANK4Original digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mark Poster Letter to Jean-Francois Lyotard, December 8, 1988

open access: yes
Original file path: CTI_emails\CT-1988\LYOTARDOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation. Original file
Poster, Mark
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mark Poster Letter to Geoffrey Hartman, June 17, 1992

open access: yes
Original file path: CTI_emails\CT-1992\HARTMANOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation. Original file
Poster, Mark
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Mark Poster Letter to Ernesto Laclau, April 5, 1990

open access: yes
Original file path: CTI_emails\CT-1990\LACLAU3Original digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation. Original file
Poster, Mark
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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