Results 161 to 170 of about 656,203 (309)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Mark Poster Letter to Jean Baudrillard, February 6, 1998

open access: yes
Original file path: CTI_emails\CT-1998\Baudrillard.wpdOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation ...
Poster, Mark
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Mark Poster Letter to Teresa de Lauretis, October 13, 1988

open access: yes
Original file path: CTI_emails\CT-1988\LAURETISOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mark Poster Letter to Jacques Derrida, March 5, 1990

open access: yes
Original file path: CTI_emails\CT-1990\DERRIDAOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation. Original file
Poster, Mark
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Mark Poster Letter to Zsuzsa Baross, January 16, 1992

open access: yes
Original file path: CTI_emails\CT-1992\BAROSSOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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