Results 141 to 150 of about 656,203 (309)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Mark Poster Letter to Wolfgang Iser, October 18, 1991

Original file path: CTI_emails\CT-1991\ISEROriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

Highlights from the Brain Conference 2026. [PDF]

Brain Commun
Marescotti M.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Mark Poster Letter to Dominique Janicaud, February 01, 1988

Original file path: CTI_emails\CT-1988\JANICAUXOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Mark Poster Letter Gayatri Spivak, April 22, 1998

Original file path: CTI_emails\CT-1998\spivak.wpdOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core  

High school science fair: Characterizing student communication and presentation practices and their association with SEF outcomes. [PDF]

PLoS One
Grinnell F, Dalley S, Reisch J.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Mark Poster Letter to Andreas Huyssen, September 16, 1988

Original file path: CTI_emails\CT-1988\HUYSSENOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation. Original file
Poster, Mark
core