Results 81 to 90 of about 656,203 (309)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Considérations sur l’évolution de l’affiche communiste vers la standardisation [PDF]
Codrul Cosminului, 2010 Using poster to spread Marxist-Leninist ideology, but also to popularize “grand achievements of the popular regime” represented only one aspect of the phenomenon of propaganda in our country. For Romania's postwar history the poster is a genuine document,
Ioan Tomoiagă
doaj
Original file path: CTI_emails\CT-1992\POSTEROriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Didasc@lia: didáctica y educación, 2010 The posters and conceptual maps constitute resources used in different ways in teaching and didactic investigation: in the diagnosis to reveal previous ideas or for contrasting the obtained results by different groups of students.
Ana María Jalil, Carmen Peme-Aranega
doaj
Original file path: CTI_emails\CT-1999\ctivita.wpdOriginal digital files were selected and transferred by Mark Poster to UCI Libraries via a portable hard drive then converted to PDF/A format by UCI Libraries' staff for access and preservation.
Poster, Mark
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source