Fibronectin has multifunctional roles in posterior capsular opacification (PCO) [PDF]
Matrix Biology, 2020 Fibrotic posterior capsular opacification (PCO), one of the major complications of cataract surgery, occurs when lens epithelial cells (LCs) left behind post cataract surgery (PCS) undergo epithelial to mesenchymal transition, migrate into the optical axis and produce opaque scar tissue.
Mahbubul H Shihan +2 more
exaly +5 more sources
Spatiotemporal dynamics of canonical Wnt signaling during embryonic eye development and posterior capsular opacification (PCO). [PDF]
Exp Eye Res, 2018 The appropriate spatial and temporal regulation of canonical Wnt signaling is vital for eye development. However, the literature often conflicts on the distribution of canonical Wnt signaling in the eye. Here, using a sensitive mouse transgenic reporter line, we report a detailed re-evaluation of the spatiotemporal dynamics of canonical Wnt signaling ...
Wang Y +6 more
europepmc +4 more sources
ODS Pseudophakia + Posterior Capsular Opacification (PCO): Case Report
Professional Health JournalPosterior capsular opacity (PCO), also known as after cataract, is a complication of cataract surgery that manifests as an opacity that persists or develops after extracapsular lens extraction.
Khilda Safinatin Najiyah, Faozan
doaj +2 more sources
Paeonol suppresses epithelial-mesenchymal transition-driven posterior capsular opacification through activation of AMPK signaling [PDF]
International Journal of OphthalmologyAIM: To determine whether paeonol (Pae), a naturally occurring phenolic compound, can serve as an effective pharmacological inhibitor of posterior capsular opacification (PCO). METHODS: A rat model of cataract surgery—induced PCO was established, and Pae
Qing Wang +8 more
doaj +2 more sources
Vanishing PCO- Recurrent posterior capsular opacification
TNOA Journal of Ophthalmic Science and Research, 2023 Bala Saraswathy, Kalpana Narendran
doaj +2 more sources
Unanswered questions regarding the pathogenesis of late onset posterior capsular opacification [PDF]
Frontiers in OphthalmologyFollowing extracapsular cataract extraction, residual lens epithelial cells (LECs) are induced to express pro-inflammatory genes within hours of surgery, then begin to proliferate while migrating to populate denuded areas of the lens capsule.
S. M. Rakib-Uz-Zaman +2 more
doaj +2 more sources
Bioactive Materials, 2022 Posterior capsular opacification (PCO), the most common complication after cataract surgery, is caused by the proliferation, migration and differentiation of residual lens epithelial cells (LECs) on the surface of the intraocular lens (IOL).
Siqing Zhu +5 more
doaj +3 more sources
Refraction and Intraocular Pressure Changes After YAG Laser Posterior Capsulotomy in Posterior Capsular Opacification [PDF]
Al-Azhar International Medical Journal, 2022 Background: Posterior capsular opacification (PCO), often known as “secondary cataract” PCO is Formed by remained sub-capsular epithelial lens cells which migrate, proliferate and differentiate leading to opacity with drop of vision and other visual ...
Mohamed Ibrahim +2 more
doaj +1 more source
Treatment classification of posterior capsular opacification (PCO) using automated ground truths
CoRR, 2022 Determination of treatment need of posterior capsular opacification (PCO)-- one of the most common complication of cataract surgery -- is a difficult process due to its local unavailability and the fact that treatment is provided only after PCO occurs in the central visual axis.
Raisha Shrestha +5 more
openaire +2 more sources
An Optical Section-Assisted In Vivo Rabbit Model for Capsular Bend and Posterior Capsule Opacification Investigation. [PDF]
PLoS ONE, 2016 To establish an optical section-assisted in vivo rabbit model for capsular bend and posterior capsule opacification (PCO) investigation.A total of 10 rabbits underwent phacoemulsification surgery and intraocular lens (IOL) implantation.
Pingjun Chang +9 more
doaj +1 more source