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Posterior capsule opacification

Experimental Eye Research, 2009
Posterior Capsule Opacification (PCO) is the most common complication of cataract surgery. At present the only means of treating cataract is by surgical intervention, and this initially restores high visual quality. Unfortunately, PCO develops in a significant proportion of patients to such an extent that a secondary loss of vision occurs.
I Michael Wormstone
exaly   +5 more sources

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Posterior capsule opacification

Survey of Ophthalmology, 1992
A complication of extracapsular cataract extraction with or without posterior chamber intraocular lens (PC-IOL) implantation is posterior capsule opacification. This condition is usually secondary to a proliferation and migration of residual lens epithelial cells.
Ehud Assia, Kerry D Solomon, E I Assia
exaly   +3 more sources

Posterior Capsule Opacification in Pseudophakic Eyes

Ophthalmology, 1983
Posterior capsule opacification following extracapsular cataract extraction is a manifestation of proliferation of anterior lens epithelium onto the posterior capsule. In addition to Elschnig pearl formation, vision is decreased in two ways. Multiple layers of proliferated epithelium produce a frank opacity.
Marco Zarbin, P J McDonnell
exaly   +3 more sources

Posterior capsule opacification: What's in the bag? [PDF]

Progress in Retinal and Eye Research, 2021
Cataract, a clouding of the lens, is the most common cause of blindness in the world. It has a marked impact on the wellbeing and productivity of individuals and has a major economic impact on healthcare providers.
Michael Wormstone
exaly   +2 more sources

Experimental models for posterior capsule opacification research [PDF]

Experimental Eye Research, 2016
Millions of people worldwide are blinded due to cataract formation. At present the only means of treating a cataract is through surgical intervention. A modern cataract operation involves the creation of an opening in the anterior lens capsule to allow ...
Michael Wormstone
exaly   +2 more sources

Posterior capsule opacification and anterior capsule opacification

Current Opinion in Opthalmology, 2001
Posterior capsule opacification (PCO) is still the most frequent complication of cataract surgery. A variety of studies has led to a better understanding of the pathogenesis of PCO, and strategies of molecular biology have produced new therapeutic options, such as immunological techniques or gene therapeutic approaches.
E, Bertelmann, C, Kojetinsky
openaire   +2 more sources

Posterior Capsule Opacification

Archives of Ophthalmology, 1985
Posterior capsule opacification results from migration of lens epithelial cells onto the posterior capsule, where they produce collagen and contract to cause wrinkling of the capsule. We have designed an in vitro model that reproduces the process of opacification.
P J, McDonnell, S L, Rowen, B M, Glaser, M, Sato   +3 more
openaire   +2 more sources

Capsulorhexis size and posterior capsule opacification

Journal of Cataract and Refractive Surgery, 1996
Posterior capsule opacification (PCO) after intraocular lens (IOL) implantation has a multifactored pathogenesis. Capsulorhexis and capsular bag implantation of a one-piece, biconvex poly(methyl methacrylate) (PMMA) IOL are likely to reduce the PCO incidence.
RAVALICO, GIUSEPPE, TOGNETTO, DANIELE, Palomba M. A., Busatto p., Baccara F.   +4 more
openaire   +3 more sources

Posterior capsule opacification

Current Opinion in Ophthalmology, 2006
This paper assesses the factors that contribute to the formation of an effective capsular bend as a deterrent to posterior capsule opacification. Its goal is to assist the practicing ophthalmologist in separating current understanding of this process from various working models previously proposed.While a square-edge design appreciably improves ...
openaire   +2 more sources

Posterior Capsule Opacification

2010
Posterior capsule opacification (PCO), also known as after-cataract and secondary cataract, is the most prevalent complication following cataract surgery. The basis of the condition is a pronounced wound-healing response from residual lens epithelial cells, which colonize the lens posterior capsule, deform the matrix, and form cell aggregates.
Judith West-Mays, Heather Sheardown
openaire   +2 more sources