Results 71 to 80 of about 7,414 (241)

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

The Prophylactic Effect of Dexmedetomidine 0.008% Versus Brimonidine 0.2% on IOP Elevation After Nd: YAG Laser Capsulotomy

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Posterior capsule opacification (PCO) is a common post‐cataract surgery complication treated with Nd:YAG laser posterior capsulotomy, which may cause intraocular pressure (IOP) spikes and threaten vision. Brimonidine and apraclonidine are widely used to prevent such elevations.
Parisa Zakeri, Ghodrat Akhavanakbari, Habib Ojaghi, Firouz Amani   +3 more
wiley   +1 more source

Biomaterial Influence on Intraocular Lens Performance: An Overview

Journal of Ophthalmology, 2018
There is strong evidence that the IOL material is the factor having the greatest impact on posterior capsule opacification (PCO), anterior capsule opacification (ACO) development, and glistening formation after cataract surgery, even though there are ...
Cari Pérez-Vives
doaj   +1 more source

Posterior capsule opacification following 20- and 23-gauge phacovitrectomy (posterior capsule opacification following phacovitrectomy) [PDF]

Eye, 2012
To compare the development of posterior capsule opacification (PCO) for idiopathic epi-retinal membrane cases between 20- and 23-gauge phacovitrectomy.Cataract surgery of phacoemulsification with the SA60AT implantation and 20- or 23-gauge vitrectomy was performed for 20 patients in both groups.
T, Iwase, B C, Oveson, Y, Nishi
openaire   +2 more sources

Incidence of posterior capsule opacification in patients submitted to phacoemulsification and expandable acrylic intraocular lens implantation [PDF]

, 2006
OBJETIVO: Avaliar prospectivamente os resultados das lentes intra-oculares de polímeros expansíveis implantadas em pacientes submetidos à facoemulsificação, quanto à incidência de opacificação de cápsula posterior, levando em consideração a ...
Hilton Arcoverde Gonçalves de Medeiros, Marcos Ávila, Medeiros, Hilton Arcoverde Gonçalves de, Procópio Miguel dos Santos, Santos, Procópio Miguel dos, Ávila, Marcos   +5 more
core   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

Aging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou, Wanqian Li, Jiaojiao Zhang, Chao Cen, Wanqiu Zheng, Ruonan Li, Hong Cheng, Liang Liang, Juan Kang, Wenjuan Wan, Ke Hu, Shijie Zheng   +11 more
wiley   +1 more source

Recurrent posterior capsule opacification in an adult

Kerala Journal of Ophthalmology
A 59-year-old male presented with diminished vision in the right eye (OD) after undergoing cataract surgery 4 years back. One year later, he developed posterior capsular opacification, for which laser capsulotomy was done.
V R Vivekanandan, K Jezeela, A Odayappan
doaj   +1 more source

The influence of size and shape of Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on visual acuity and refraction

SVU - International Journal of Medical Sciences, 2018
Background: Posterior capsule opacification is the most common complication of cataract surgery and results from the proliferation and migration of residual lenticular epithelial cells.
Ayat A. Aboelmaged, Mohamed S. Abdelrahman, Ahmed H. Mohamed, Osama A. El-Soghair   +3 more
doaj   +1 more source

Diagnosis and Metabolic Management of Adult Refsum Disease: Guidance From the Medical and Scientific Committee of Global DARE (Defeat Adult Refsum Everywhere)

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Adult Refsum disease (ARD; OMIM 266510) is a degenerative autosomal recessive condition typically diagnosed in adulthood. It affects visual, auditory and nervous system function. It is characterised by plasma, neuro‐ophthalmological and adipose tissue accumulation of the dietary‐derived phytanic acid (PA).
Radha Ramachandran, Raphael Buttigieg, Florian Eichler, Bart P. Leroy, Omar Mahroo, Rachel M. Huckfeldt, Sarah Firman, Eleanor Baldwin, Kristie DeMarco, Susan Kuranoff, Amena Fine, Reinhard Klingel, Sacha Ferdinandusse, Joseph G. Hacia, Ronald J. Wanders, Anthony S. Wierzbicki   +15 more
wiley   +1 more source

Posterior Capsule Opacification: Experimental Analyses

Ophthalmic Research, 2009
The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different clinical approaches to extracapsular cataract extraction currently employed. Posterior capsule opacification developed in all experimental animals within 6 weeks of the operation.
M G, Odrich, S J, Hall, B V, Worgul, S L, Trokel, F J, Rini   +4 more
openaire   +2 more sources