Results 271 to 280 of about 122,744 (337)

Combined impact of gray and superficial white matter abnormalities: Implications for epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant focal epilepsy is associated with abnormalities in the brain in both gray matter (GM) and superficial white matter (SWM). However, it is unknown if both types of abnormalities are important in supporting seizures. Here, we test if surgical removal of GM and/or SWM abnormalities relates to post‐surgical seizure outcome ...
Csaba Kozma, Jonathan Horsley, Gerard Hall, Callum Simpson, Jane de Tisi, Anna Miserocchi, Andrew W. McEvoy, Sjoerd B. Vos, Gavin P. Winston, Yujiang Wang, John S. Duncan, Peter N. Taylor   +11 more
wiley   +1 more source

Functional network dynamics in photosensitive epilepsy depend on stimulation frequency and photoparoxysmal electroencephalographic response

Epilepsia, EarlyView.
Abstract Objective Photosensitive epilepsy (PSE) is a reflex epilepsy, where abnormal electroencephalographic (EEG) responses are induced by photic stimulation. Photosensitivity is classified into four types based on the propagation of the brain's response to visual stimuli.
Lili Timar, Sina Deplazes, Julia Bothmann, Roland Renzel, Debora Ledergerber, Tena Dubcek, Lukas Imbach   +6 more
wiley   +1 more source

HD‐EEG source imaging with simultaneous SEEG recording in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective This study aimed to assess the complementary role of high‐density electroencephalography (HD‐EEG)–based electrical source imaging (ESI) in localizing the seizure‐onset zone (SOZ) during ictal events and the irritative zone (IZ) during the interictal period, using simultaneous acquired stereo‐EEG (SEEG) recordings as a reference.
Shenglin Hao, Haifeng Zhao, Ziyi Feng, Wei Liu, Chao Zhang, Hang Ping, Qiang Zhou, Bomin Sun, Shikun Zhan, Chunyan Cao   +9 more
wiley   +1 more source

Novel neuropathological observations in an adult with Dravet syndrome

Epilepsia, EarlyView.
Abstract Dravet syndrome (DS) is a developmental and epileptic encephalopathy associated with pathogenic variants in the SCN1A gene. The neuropathological features of adult DS remain poorly understood. We report the postmortem findings of a 55‐year‐old woman with DS due to a confirmed SCN1A pathogenic variant leading to Nav1.1 loss of function ...
Danielle M. Andrade, Anne S. Bassett, Quratulain ZulfiqarAli, Victor S. T. Lira, Nikolai Gil Reyes, M. Carmela Tartaglia, Alfonso Fasano, Gabor G. Kovacs   +7 more
wiley   +1 more source

Association between enlarged perivascular space (ePVS) density and stereo‐electroencephalography (SEEG) biomarkers of epileptogenicity

Epilepsia, EarlyView.
Abstract Objective We aim to explore the association between enlarged perivascular space (ePVS) density and stereo‐electroencephalography (SEEG) biomarkers of epileptogenicity. Methods We retrospectively analyzed consecutive SEEG patients from an Australian site.
Jacob Bunyamin, Benjamin Sinclair, Thanomporn Wittayacharoenpong, Parveen Sagar, William Pham, Zhibin Chen, Noam Bosak, Joshua Laing, Matthew Gutman, Martin Hunn, Patrick Kwan, Terence J. O'Brien, Meng Law, Andrew Neal   +13 more
wiley   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader, Amy S. Garrett, Steven R. Pliszka   +2 more
wiley   +1 more source

Research Review: What we have learned about the endocannabinoid system in developmental psychopathology

Journal of Child Psychology and Psychiatry, EarlyView.
Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior.
Ryann C. Tansey, Marc D. Ferger, Hilary A. Marusak, Leah M. Mayo   +3 more
wiley   +1 more source

Avoidance habit learning in adolescents and young women with anorexia nervosa: an fMRI study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Anorexia nervosa (AN), often with an onset in adolescence, is a complex eating disorder characterized by distorted body image, fear of weight gain, and extreme food restriction, leading to severe underweight. Excessive goal pursuit and avoidance behaviors have been proposed as key factors in AN, which over time may become over‐trained into ...
Julius Hennig, Ilka Boehm, Katharina Zwosta, Joseph A. King, Daniel Geisler, Hannes Ruge, Maria Seidel, Fabio Bernardoni, Inger Hellerhoff, Arne Doose, Sophie Pauligk, Henri Leschzinski, Veit Roessner, Uta Wolfensteller, Stefan Ehrlich   +14 more
wiley   +1 more source

Annual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology.
Kelsey Hagan, E. Caitlin Lloyd, Sasha Gorrell   +2 more
wiley   +1 more source