Results 191 to 200 of about 117,378 (260)

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Revascularization treatment for posterior circulation ischemic stroke: a systematic review and network meta-analysis. [PDF]

BMC Neurol
Shu H, Liang M, Long Z, Zhang W, Lv F, Hu P, Tu W, Yan T.   +7 more
europepmc   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Comparison of Functional Outcomes and Its Association With the Risk Factors in Patients With Anterior and Posterior Circulation Ischemic Stroke. [PDF]

Cureus
Yasmin R, Miah MBA, Shahidullah M, Bhuiyan MM, Hasan M, Alam SM, Dey SK, Rana MM, Huq MR.   +8 more
europepmc   +1 more source

Posterior circulation stroke

, 2011
openaire   +1 more source

Thrombolysis with Adjunctive Tirofiban in Acute Non-cardioembolic Posterior Circulation Ischemic Stroke: A Propensity Score-Matched Analysis. [PDF]

Neurol Ther
Yuan H, Du M, Zhang T, Luan Z, Sun Z, Liang Z.   +5 more
europepmc   +1 more source

Dual antiplatelet versus alteplase in anterior and posterior circulation minor stroke. [PDF]

Stroke Vasc Neurol
Cui Y, Chen HS.
europepmc   +1 more source

Posterior circulation infarcts

, 2020
openaire   +1 more source