Results 61 to 70 of about 713,452 (146)

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, Volume 13, Issue 16, 18 March 2026.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

The relationship between scleral staphyloma and choroidal thinning in highly myopic eyes: The Beijing Eye Study

, 2017
Based on the Beijing Eye Study 2011, a detailed ophthalmic examination was performed including spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging for measurement of subfoveal choroidal thickness (SFCT) and relative height ...
Qi Sheng You, Lei Shao, Wen Bin Wei, Ya Xing Wang, Ling Xiao Zhou, Liang Xu   +5 more
core   +1 more source

A Case of Knobloch Syndrome With Lens Dislocation Resembling Homocystinuria

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT We report a 39‐year‐old woman with lifelong visual impairment who presented in June 2024 with progressive visual deterioration in her right eye. Ophthalmologic evaluation revealed severe high myopia, vitreoretinal degeneration, phthisis bulbi of the left eye, and downward lens dislocation of the right eye.
Elnaz Asadollahzadeh, Ali Rezaei, Vahid Shahmaei, Mohammad‐Sadegh Johari, Mohammad Ali Sahraian   +4 more
wiley   +1 more source

Clinical and Genetic Characteristics of Free Sialic Acid Storage Disorder

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Free sialic acid storage disorder (FSASD) is a lysosomal storage disorder that results from biallelic pathogenic variants in the SLC17A5 gene. This gene codes for sialin, a 12‐transmembrane domain protein that exports the charged sugar N‐acetylneuraminic acid (Neu5Ac; sialic acid) out of the lysosome.
Zoe Wolfenson, Gabriella Grois, Ruth F. Hailemeskel, Marla Sabaii, Laryssa A. Huryn, Wadih M. Zein, Tanya Lehky, Audrey Thurm, Lisa Joseph, Eva H. Baker, Gilbert Vezina, Keith Hyland, Laura Pollard, Ellen Macnamara, Andrea Gropman, May C. Malicdan, William A. Gahl, David R. Adams, Lynne Wolfe   +18 more
wiley   +1 more source

Expanded Phenotype of PAX2‐Related Papillorenal Syndrome: A Case Featuring FSGS, Atypical Retinopathy, Cerebellar Hypoplasia, and ADHD

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Papillorenal syndrome (PAPRS), or renal coloboma syndrome, is a rare autosomal dominant disorder caused by PAX2 mutations. It classically manifests with renal hypodysplasia and optic nerve anomalies. However, recent literature suggests an expanding phenotypic spectrum.
Nadira Sultana, Abdullah Al Mamun, Afroza Begum   +2 more
wiley   +1 more source

WF-OCT image of a highly myopic eye with peripapillary staphyloma and a scleral inward protrusion.

, 2019
(A) Fundus photograph of the right eye of an 11-year-old girl with an axial length of 26.8 mm showing peripapillary diffuse chorioretinal atrophy (PDCA).
Kyoko Ohno-Matsui (159383), Kengo Uramoto (6818075), Takeshi Yoshida (802249), Kosei Shinohara (4060753), Tae Yokoi (334823), Noriko Tanaka (174050), Shintaro Horie (446873), Yuka Onishi (6818078), Hiroyuki Takahashi (281673)   +8 more
core   +1 more source

Associations between Intraocular Pressure or Glaucoma Medication with Axial Length and Pathologic Myopia Incidence and Progression

Ophthalmology Science
Objective: To investigate the relationship between intraocular pressure (IOP) and antiglaucoma medications on both the incidence and progression of myopic macular degeneration (MMD), posterior staphyloma and axial length (AXL) elongation in highly myopic
Maverick Wenhao Wong, MBBS, Huanye Li, BEng, Yee Shan Dan, MSc, Samantha CN. Lor, Raphael Soh, MBBS, Quan V. Hoang, MD, PhD, Rachel S. Chong, MBBS, PhD   +6 more
doaj   +1 more source

SFM‐UNet: A Spatial‐Frequency Memorizable Model for Posterior Sclera OCT Analysis

IET Image Processing, Volume 20, Issue 1, January/December 2026.
First, we propose an enhanced cross slice spatial frequency storage block (ECSFMB) module, which can better capture the continuity between multiple slices in 3D images, improves the consistency and accuracy of segmentation. Second, we propose a new variant of UNet, SFM (spatial frequency memory) UNet, which fully utilizes the periodicity and globality ...
Jiashu Xu, Fanglin Chen
wiley   +1 more source

Anatomical and functional results of macular hole retinal detachment surgery in patients with high myopia and posterior staphyloma treated with perfluoropropane gas or silicone oil

, 2013
To evaluate the use of perfluoropropane gas (C3F8) versus silicone oil (SO) for retinal detachment secondary to macular hole in patients with high myopia and posterior ...
Mancino, R, Ciuffoletti, E, Aiello, F, Cerulli, L, NUCCI, CARLO, Cedrone, C, Nucci, C, MANCINO, RAFFAELE, Martucci, A, CERULLI, LUCIANO, AIELLO, FRANCESCO   +10 more
core   +1 more source

Necrotizing Scleritis in Granulomatosis With Polyangiitis: A Clinical Challenge for an Ophthalmologists

Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.
Introduction Granulomatosis with polyangiitis (GPA) is a granulomatous disease with multisystem involvement, frequently with ocular manifestations. It can lead to ocular morbidity due to tissue melting and necrosis. Case Description A 35‐year‐old male presented with a painless nodular lesion in the left eye, along with gradual diminution of vision and ...
Poonam Lavaju, Sangeeta Shah, Ashmita Jha, Binay Kamat, Kushal Gurung, Huban Atilla   +5 more
wiley   +1 more source