Results 151 to 160 of about 777,586 (252)

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu   +6 more
wiley   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Neurological Manifestations in Whipple's Disease: A Scoping Review of Clinical Features, Laboratory Findings, and Neuroimaging Characteristics of 111 Cases

open access: yesEuropean Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Whipple disease (WD) is a rare, potentially fatal infection caused by Tropheryma whipplei (TW). Central Nervous System involvement (CNS‐WD) is a severe complication of WD with a challenging diagnosis, due to limited data integrating neurological features, imaging, cerebrospinal fluid analysis, PCR, and intestinal histopathology ...
Lucia Moro   +7 more
wiley   +1 more source

CRB1-associated retinal dystrophy presenting as self-resolving opsoclonus and posterior uveitis. [PDF]

open access: yesAm J Ophthalmol Case Rep, 2022
Li AS   +5 more
europepmc   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

open access: yesInternational Journal of Dermatology, Volume 65, Issue 10, Page 2018-2027, October 2026.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo   +2 more
wiley   +1 more source

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