Results 131 to 140 of about 392,797 (346)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Safer Sex und Solidarität. Die Sammlung internationaler Aidsplakate im Deutschen Hygiene-Museum
Zeithistorische Forschungen, 2013 Susanne Roeßiger
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Les paysages touristiques dans l’imagerie des affiches suisses (fin XIXe siècle-milieu XXe siècle)
Diacronie. Studi di Storia Contemporanea, 2018 One hundred Swiss railroad posters are analyzed. They run from the end of 19th century to the beginning of the mass tourism, before the generalized use of the photography. They are draftsmen’s work.
Martine Tabeaud est Professeur de Géographie à l’Université Paris 1 Panthéon-Sorbonne, directrice de l’UMR CNRS 8185 ENeC (Espaces, Nature et Culture) et co-fondatrice du Réseau Perception du climat. Elle a soutenu une thèse de doctorat sur Climatologie descriptive et imagerie satellitaire et une thèse d’État sur L’Atlantique tropical austral: l’eau atmosphérique et le climat en milieu océanique. Elle a, entre autres, publié l’ouvrage de référence Climatologie générale (Paris, Armand Colin, 1998) cinq fois réédité, et, plus récemment (avec KISLOV, Alexandre) Le changement climatique : Europe, Asie septentrionale, Amérique du nord (Allonzier-la-Caille, Eurcasia 2011) ainsi que Le nuage (Paris, L’Harmattan, 2014). En 2017 – avec De LA SOUDIÈRE, Martin, VASAK, Anouchka – elle a dirigé le numéro spécial de «Communications» sur Le temps qu’il fait. Elle a publié dans la revue «Espaces», en 2007, un article intitulé : « L’imagerie stéréotypée des brochures des offices de tourisme », 246, 2007, pp. 31-35. +1 more
doaj
Poster 2011: A DNA vaccine immunotherapy for japanese red cedar allergy [PDF]
, 2014 Lawrence M. Weiner +3 more
openalex +1 more source