Results 191 to 200 of about 797,280 (374)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
"Mugshot" Banned Books Week posters [PDF]
, 2017 These posters make students aware of books that have been banned throughout history and encourage students to exercise their freedom to read without ...
Mei, Qian
core
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
"Welcome Back" Spring 2017 posters [PDF]
, 2017 These posters were created to welcome BU students to the spring semester of ...
Yang, Hanna
core
Les paysages touristiques dans l’imagerie des affiches suisses (fin XIXe siècle-milieu XXe siècle)
Diacronie. Studi di Storia Contemporanea, 2018 One hundred Swiss railroad posters are analyzed. They run from the end of 19th century to the beginning of the mass tourism, before the generalized use of the photography. They are draftsmen’s work.
Martine Tabeaud est Professeur de Géographie à l’Université Paris 1 Panthéon-Sorbonne, directrice de l’UMR CNRS 8185 ENeC (Espaces, Nature et Culture) et co-fondatrice du Réseau Perception du climat. Elle a soutenu une thèse de doctorat sur Climatologie descriptive et imagerie satellitaire et une thèse d’État sur L’Atlantique tropical austral: l’eau atmosphérique et le climat en milieu océanique. Elle a, entre autres, publié l’ouvrage de référence Climatologie générale (Paris, Armand Colin, 1998) cinq fois réédité, et, plus récemment (avec KISLOV, Alexandre) Le changement climatique : Europe, Asie septentrionale, Amérique du nord (Allonzier-la-Caille, Eurcasia 2011) ainsi que Le nuage (Paris, L’Harmattan, 2014). En 2017 – avec De LA SOUDIÈRE, Martin, VASAK, Anouchka – elle a dirigé le numéro spécial de «Communications» sur Le temps qu’il fait. Elle a publié dans la revue «Espaces», en 2007, un article intitulé : « L’imagerie stéréotypée des brochures des offices de tourisme », 246, 2007, pp. 31-35. +1 more
doaj
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source