Results 71 to 80 of about 6,056 (173)

What is the addiction risk associated with tramadol? [PDF]

open access: yes, 2005
Tramadol (Ultram, generic and with acetaminophen in Ultracet) carries a risk of substance abuse (strength of recommendation [SOR]: B, based on case report surveillance programs).
Mackler, Leslie, McDiarmid, Todd
core  

Nelarabine Associated Myotoxicity and Rhabdomyolysis

open access: yesCase Reports in Hematology, 2015
Nelarabine (ara-G; Arranon; compound 506U78) is an antineoplastic purine analog used for the treatment of refractory or relapsed T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).
Mahnur Haider   +2 more
doaj   +1 more source

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma   +17 more
wiley   +1 more source

Post-Market Surveillance Study of a Skull Flap Fixation Device: Cranfixer

open access: yesIranian Journal of Neurosurgery, 2019
Background and Aim: Cranfixer was approved in 2017 by the Food and Drug Administration of Iran as a skull flap fixation and also a burr hole cover.
Seyed Roholah Ghodsi   +3 more
doaj  

Glycoprotein IIb/IIIa Inhibitors Use and Outcome after Percutaneous Coronary Intervention for Non-ST Elevation Myocardial Infarction [PDF]

open access: yes, 2014
Aims. We investigate the effect of glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitors on long-term outcomes following percutaneous coronary intervention (PCI) after non-ST elevation myocardial infarction (NSTEMI). Meta-analyses indicate that these agents are
Antoniou, S   +9 more
core   +4 more sources

The Challenges of Vascular Implants: Regulatory Strategies and Biological Responses

open access: yesSmall Science, Volume 5, Issue 12, December 2025.
Implantable vascular devices are revolutionizing the management of cardiovascular diseases, such as heart failure, by enabling real‐time monitoring and individualized therapy. However, their potential is challenged by regulatory constraints and biological barriers, as device implantation into a vessel can trigger inflammation, thrombosis, and long‐term
Serena Babboni   +5 more
wiley   +1 more source

Incentivizing the Utilization of Pharmacogenomics in Drug Development [PDF]

open access: yes, 2012
Pharmacogenomics, the study and development of compounds according to how an individual’s genes affects the body’s response to drugs, holds enormous promise for increasing the safety and efficiency of drug development while decreasing adverse reactions ...
Koch, Valerie Gutmann
core   +1 more source

In vitro and in vivo postmarketing surveillance of valsartan, alone or in combination with amlodipine or hydrochlorthiazide, among Palestinian hypertensive patients

open access: yesTherapeutics and Clinical Risk Management, 2016
Abdel Naser Zaid,1 Masshour Ghanem,2 Dua’a Shweiki,1 Hala Shtewi,1 Raja’ Shaheen,1 Sondos Al Helaly,1 Zeina Khayyat,1 Rowa’a Al Ramahi,1 Sa’ed H Zyoud1 1Department of Pharmacy, Faculty of Medicine & Health Sciences, An-Najah ...
Zaid AN   +8 more
doaj  

Reações adversas a medicamentos em pediatria: uma revisão sistemática de estudos prospectivos Adverse drug reactions in pediatrics: a systematic review of prospective studies

open access: yesRevista Brasileira de Saúde Materno Infantil, 2004
O objetivo desta revisão foi explorar e comparar as informações derivadas de estudos prospectivos sobre a incidência de reações adversas a medicamentos (RAM) em pediatria, publicados de janeiro de 1966 a novembro de 2003 em revistas indexadas nas bases ...
Djanilson Barbosa dos Santos   +1 more
doaj   +1 more source

Melanosis Secondary to Drugs: A Real‐World Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS)

open access: yesSkin Research and Technology, Volume 31, Issue 12, December 2025.
ABSTRACT Background Melanosis is an acquired hyperpigmentation disorder that can be associated with the use of medications; timely identification and discontinuation of relevant medications is an important aspect of clinical management. Objective This study investigates the relationship between melanosis and drug exposure based on data from the FDA ...
Yilin Zhao   +3 more
wiley   +1 more source

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