Results 71 to 80 of about 25,533 (219)

Information and communication technology solutions for outdoor navigation in dementia [PDF]

open access: yes, 2016
INTRODUCTION: Information and communication technology (ICT) is potentially mature enough to empower outdoor and social activities in dementia. However, actual ICT-based devices have limited functionality and impact, mainly limited to safety. What is an
Aloulou   +59 more
core   +1 more source

Safety, Immunogenicity and Interchangeability of Biosimilar Monoclonal Antibodies and Fusion Proteins : A Regulatory Perspective [PDF]

open access: yes, 2021
Publisher Copyright: © 2021, The Author(s).Background: Biosimilars have been used for 15 years in the European Union (EU), and have been shown to reduce costs and increase access to important biological medicines.
Barry, Sean   +4 more
core   +1 more source

Reações adversas a medicamentos em pediatria: uma revisão sistemática de estudos prospectivos Adverse drug reactions in pediatrics: a systematic review of prospective studies

open access: yesRevista Brasileira de Saúde Materno Infantil, 2004
O objetivo desta revisão foi explorar e comparar as informações derivadas de estudos prospectivos sobre a incidência de reações adversas a medicamentos (RAM) em pediatria, publicados de janeiro de 1966 a novembro de 2003 em revistas indexadas nas bases ...
Djanilson Barbosa dos Santos   +1 more
doaj   +1 more source

Understanding the Mechanism of Cardiotoxicity Induced by Nanomaterials: A Comprehensive Review

open access: yesSmall Science, Volume 5, Issue 5, May 2025.
This review provides a bibliometric analysis for understanding the study of nanotoxicity on cardiovascular health. It begins by outlining the pathways through which nanomaterials enter the cardiovascular system, followed by a summary of the mechanisms underlying nanomaterial‐induced cardiotoxicity.
Zaiyong Zheng   +7 more
wiley   +1 more source

In vitro and in vivo postmarketing surveillance of valsartan, alone or in combination with amlodipine or hydrochlorthiazide, among Palestinian hypertensive patients

open access: yesTherapeutics and Clinical Risk Management, 2016
Abdel Naser Zaid,1 Masshour Ghanem,2 Dua’a Shweiki,1 Hala Shtewi,1 Raja’ Shaheen,1 Sondos Al Helaly,1 Zeina Khayyat,1 Rowa’a Al Ramahi,1 Sa’ed H Zyoud1 1Department of Pharmacy, Faculty of Medicine & Health Sciences, An-Najah ...
Zaid AN   +8 more
doaj  

Current Evidence on Cabazitaxel for Prostate Cancer Therapy: A Narrative Review

open access: yesInternational Journal of Urology, Volume 32, Issue 5, Page 475-487, May 2025.
ABSTRACT The incidence of prostate cancer (PC) has recently increased in Japan. Androgen deprivation therapy (ADT) has been a key treatment in patients with castration‐sensitive PC (CSPC); however, resistance typically emerges through multiple mechanisms, leading to metastatic castration‐resistant PC (mCRPC).
Kazuhiro Suzuki   +5 more
wiley   +1 more source

Avaliação do sistema brasileiro de vigilância de eventos adversos pós-vacinação Evaluation of the Brazilian surveillance system for adverse events following vaccination

open access: yesRevista Brasileira de Epidemiologia, 2011
OBJETIVOS: Descrever e avaliar o Sistema brasileiro de vigilância passiva de eventos adversos pós-vacinação (SPVEAPV). MÉTODOS: A descrição e avaliação do SPVEAPV fundamentaram-se nas notificações de eventos adversos pós-vacina Tetravalente ou DTwP/Hib -
Sandra Aparecida Moreira Gomes Monteiro   +2 more
doaj   +1 more source

What is the addiction risk associated with tramadol? [PDF]

open access: yes, 2005
Tramadol (Ultram, generic and with acetaminophen in Ultracet) carries a risk of substance abuse (strength of recommendation [SOR]: B, based on case report surveillance programs).
Mackler, Leslie, McDiarmid, Todd
core  

Applications of Artificial Intelligence in Drug Repurposing

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
Artificial intelligence algorithms are transforming drug repurposing by revealing new therapeutic targets and mechanisms. This review highlights the integration of AI frameworks, multimodal datasets, and advanced optimization methods, accelerating the discovery of new indications for existing drugs.
Zhaoman Wan   +6 more
wiley   +1 more source

Incentivizing the Utilization of Pharmacogenomics in Drug Development [PDF]

open access: yes, 2012
Pharmacogenomics, the study and development of compounds according to how an individual’s genes affects the body’s response to drugs, holds enormous promise for increasing the safety and efficiency of drug development while decreasing adverse reactions ...
Koch, Valerie Gutmann
core   +1 more source

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