Results 101 to 110 of about 179,279 (289)

Trends in Rheumatoid Arthritis Mortality Among Postmenopausal Women in the United States, 1999–2023

open access: yesiMetaMed, EarlyView.
RA‐related mortality among U.S. postmenopausal women has markedly declined since 1999. Despite this overall progress, significant inequalities by race, region, and age highlight ongoing challenges in achieving equitable health outcomes. ABSTRACT Rheumatoid arthritis (RA) disproportionately affects postmenopausal women, who are at an increased risk of ...
Yuhui Zhao   +4 more
wiley   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

open access: yesiMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang   +8 more
wiley   +1 more source

Cost-effectiveness analysis of Chinese patent medicines for the treatment of postmenopausal osteoporosis in China

open access: yesFrontiers in Public Health
IntroductionEvidence indicates that Chinese patent medicines can significantly increase bone mass in patients with osteoporosis and alleviate symptoms associated with low bone density.
Cong Wang   +4 more
doaj   +1 more source

Move beyond free radical theory of aging

open access: yesiMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

open access: yesiMetaOmics, EarlyView.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu   +14 more
wiley   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

open access: yesInterdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao   +12 more
wiley   +1 more source

Modeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study

open access: yesCancer Management and Research, 2019
Anwar E Ahmed,1,2 Donna K McClish,3 Thamer Alghamdi,4 Abdulmajeed Alshehri,4 Yasser Aljahdali,4 Khalid Aburayah,4 Abdulrahman Almaymoni,4 Monirah Albaijan,1 Hamdan Al-Jahdali,1,4–6 Abdul Rahman Jazieh4–6 1King Abdullah International Medical ...
Ahmed AE   +9 more
doaj  

The role of ferroptosis in osteoporosis: a cellular perspective on osteoblast, osteoclast and osteocyte dysfunction

open access: yesFrontiers in Endocrinology
Osteoporosis is characterized by an imbalance between bone resorption and bone formation, leading to the loss of both trabecular and cortical bone mass, ultimately resulting in an increased risk of fractures. Osteoporosis represents a major global health
Aysha Bakari Murusuri, Jun Tang
doaj   +1 more source

Mediterranean diet for breast cancer prevention and treatment in postmenopausal women [PDF]

open access: gold, 2015
Elżbieta Potentas   +2 more
openalex   +1 more source

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