Results 111 to 120 of about 206,257 (301)

Comparison of clinicopathological features and treatments between pre- and postmenopausal female breast cancer patients – a retrospective study

open access: yes, 2019
Introduction: To find out if there are clinical and biological differences in breast cancer characteristics of premenopausal and postmenopausal women.
Fazlı Erdoğan   +9 more
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Emerging treatments for postmenopausal osteoporosis – focus on denosumab

open access: yes, 2009
Piet GeusensDepartment of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands and Biomedical Research Institute, University Hasselt, BelgiumAbstract: The pathway of the receptor activator of ...
Piet Geusens
core   +1 more source

Vitamin K2 ameliorates pregnancy‐ and lactation‐associated osteopenia and postpartum depression

open access: yesiMeta, EarlyView.
Vitamin K2 (VitK2) supplementation ameliorates comorbid pregnancy‐ and lactation‐associated osteopenia (PLO) and postpartum depression (PPD). These improvements are accompanied by reduced relative abundance of Bacteroides uniformis (B. uniformis) and lower serum deoxycholic acid (DCA) levels. DCA inhibits osteoblast differentiation, promotes osteoclast
Wanqiong Yuan   +21 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

The role of ferroptosis in osteoporosis: a cellular perspective on osteoblast, osteoclast and osteocyte dysfunction

open access: yesFrontiers in Endocrinology
Osteoporosis is characterized by an imbalance between bone resorption and bone formation, leading to the loss of both trabecular and cortical bone mass, ultimately resulting in an increased risk of fractures. Osteoporosis represents a major global health
Aysha Bakari Murusuri, Jun Tang
doaj   +1 more source

Postmenopausal Hypertension

open access: yes, 2010
After menopause, blood pressure increases in women. However, the underlying mechanisms responsible for postmenopausal hypertension are not completely understood. This study was conducted to determine the role that the renin-angiotensin system (RAS) plays
Radu Iliescu   +5 more
core   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li   +11 more
wiley   +1 more source

Modeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study

open access: yesCancer Management and Research, 2019
Anwar E Ahmed,1,2 Donna K McClish,3 Thamer Alghamdi,4 Abdulmajeed Alshehri,4 Yasser Aljahdali,4 Khalid Aburayah,4 Abdulrahman Almaymoni,4 Monirah Albaijan,1 Hamdan Al-Jahdali,1,4–6 Abdul Rahman Jazieh4–6 1King Abdullah International Medical ...
Ahmed AE   +9 more
doaj  

Genitourinary syndrome of menopause: efficacy and safety of vaginal combination therapy. A prospective study

open access: yesГинекология
Background. Genitourinary syndrome of menopause (GSM) significantly reduces the quality of life (QoL) of women, causing pain during sexual activity, worsening sexual function and relationships with a partner, and reducing self-esteem. Nearly 75% of women
Tatiana Y. Pestrikova   +4 more
doaj   +1 more source

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