Results 71 to 80 of about 75,138 (262)

STEP levels are unchanged in pre-frontal cortex and associative striatum in post-mortem human brain samples from subjects with schizophrenia, bipolar disorder and major depressive disorder.

PLoS ONE, 2015
Increased protein levels of striatal-enriched tyrosine phosphatase (STEP) have recently been reported in postmortem schizophrenic cortex. The present study sought to replicate this finding in a separate cohort of postmortem samples and to extend ...
Thomas A Lanz, J Julie Joshi, Veronica Reinhart, Kjell Johnson, Lonnie E Grantham, Dmitri Volfson   +5 more
doaj   +1 more source

Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Postmortem microbiological examinations are performed in forensic and medical pathology for defining uncertain causes of deaths and for screening of deceased tissue donors. Interpretation of bacteriological data, however, is hampered by false-
Markus M Heimesaat, Silvia Boelke, André Fischer, Lea-Maxie Haag, Christoph Loddenkemper, Anja A Kühl, Ulf B Göbel, Stefan Bereswill   +7 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Pig Tales: Forensic Taphonomy in Cozine Creek [PDF]

, 2019
The medicolegal community relies heavily upon determining the postmortem interval (PMI), the knowledge of how much time has elapsed since the person has died.
Cattell, Cailyn, DeVisser, Elizabeth, Hyem, Audrey   +2 more
core   +1 more source

Quantification of Maceration Changes using Post Mortem MRI in Fetuses [PDF]

, 2016
BACKGROUND: Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount.
Addison, S, Arthurs, OJ, Lally, PJ, Montaldo, P, Oliveira, V, Sebire, NJ, Taylor, AM, Thayyil, S   +7 more
core   +3 more sources

Correlation between Cellular Autophagy and Color Changes in Qinchuan Cattle Meat during Postmortem Aging [PDF]

Shipin Kexue
In order to investigate the occurrence of cellular autophagy and its effect on the meat color of Qinchuan cattle during postmortem aging, the changes in the meat color, relative myoglobin content, metmyoglobin reductase activity (MRA), beclin1 ...
LIANG Yanqun, SI Jianfang, MA Meng, GAO Shuang, LI Yalei, LUO Ruiming
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Perubahan Histologik Pada Usus Besar Hewan Coba Postmortem [PDF]

, 2016
: Cell death occurs after somatic death. The aerobic process of cells would be halted as a result of somatic death, whereas the anaerobic process will continue. Therefore, the cells do not die in a short time although the oxygen supply has been depleted.
Lapian, C. (Clifford), Wangko, S. (Sunny), Wongkar, D. (Djon)   +2 more
core  

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in alzheimer’s disease and parkinson’s disease [PDF]

, 2017
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating effects in terms of morbidity and mortality.
Chakrabarti, S., Chatterjee, U., Ganguly, G., Saso, L.   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source