Results 61 to 70 of about 437,688 (307)

Exploring a complex constellation of signaling pathways

eLife
Cells called alveolar myofibroblasts, which have a central role in the development of the lung after birth, receive an orchestrated input from a range of different signaling pathways.
Nathaniel C Nelson, Matthias C Kugler
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

POSTNATAL CHANGES.

Midwives, 2015
The shift away from midwifery’s involvement in postnatal care has implications for students – the workforce of the future. Two midwifery educators argue that there needs to be joined-up thinkingon how postnatal care is delivered.
Hall, Jenny, Lucas, G.
openaire   +1 more source

Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming. [PDF]

, 2014
BACKGROUND Maternal undernutrition leads to an increased risk of metabolic disorders in offspring including obesity and insulin resistance, thought to be due to a programmed thrifty phenotype which is inappropriate for a subsequent richer nutritional ...
Stewart Gilmour, Morris, Tiffany J., Vickers, Mark H., Nabeel A Affara, Gilmour, Stewart, Benjamin M Skinner, Sargent, Carole A., Mark H Vickers, Peter D Gluckman, Affara, Nabeel A., Ellis, Peter J.I., Skinner, Benjamin M., Peter JI Ellis, Tiffany J Morris, Carole A Sargent, Gluckman, Peter D.   +15 more
core   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Group cognitive behavioural therapy for postnatal depression : a systematic review of clinical effectiveness, cost effectiveness and value of information analyses [PDF]

, 2010
Background: Postnatal depression (PND) describes a wide range of distressing symptoms that can occur in women following childbirth. There is substantial evidence to support the use of cognitive behaviour therapy (CBT) in the treatment of depression, and
Parry, G., The group cognitive behavioural therapy for postnatal depression advisory group, A Scope, G Parry, MD Stevenson, Slade, P., P Slade, PA Sutcliffe, Booth, A., D Saxon, A Booth, Kalthenthaler, E., Sutcliffe, P. (Paul), E Kalthenthaler, Saxon, D., Scope, Alison, Stevenson, M. (Matt)   +16 more
core   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Parents' Postnatal Sense of Security: A Concept Analysis

Nursing Open
Aim Parents' postnatal sense of security is often mentioned in recent publications, but there is no consensus on its definitions and measurement. A concept analysis was conducted to clarify the definition, the attributes, antecedents and the consequences
Tieying Zeng, Lingjun Jiang, Deqing Huang, Meiliyang Wu, Aiqing Tu   +4 more
doaj   +1 more source

EFFECT OF TRANSPLACENTAL-FETAL BARRIER AND LACTATIONAL TRANSFER OF LEAD ON PROLACTIN GENE EXPRESSION, DNA FRAGMENTATION AND CHANGES IN THE BRAIN OF EXPOSED MOTHERS AND THEIR OFFSPRING IN ALBINO RATS [PDF]

Assiut Veterinary Medical Journal, 2015
The present study was conducted to report the effect of prenatal and postnatal treatment of lead (Pb) on some antioxidant defense system in cerebrum and cerebellum of dams and of their foeti, histopathological lesions and DNA fragmentation in brain of ...
A.A. KHALAF, BR. ABDEL–HALIM, WALAA A. MOSELHY, MARWA A. IBRAHIM   +3 more
doaj   +1 more source