Results 101 to 110 of about 4,270,416 (296)
Improvements of postnatal care are required by Swedish fathers
Purpose – This paper has two main aims: to explore fathers' postnatal care experiences with a specific focus on deficiencies and to investigate which service deficiencies remained important for fathers one year after childbirth.Design/methodology ...
Johansson, Margareta +6 more
core +1 more source
Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao +12 more
wiley +1 more source
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
BackgroundBoth mothers and newborns go through a critical time in their lives during the postnatal period, and the majority of deaths of mothers and neonates happen during this period.
Hana Israel Gesisa +4 more
doaj +1 more source
Exploring Australian knowledge and practice for maternal postnatal transition of care between hospital and primary care: A scoping review [PDF]
Problem Despite the significance of the perinatal period, postnatal care remains insufficient for optimising long-term health. Background The perinatal period is a vulnerable time in a woman’s life-course health trajectory.
Green, JE +5 more
core +1 more source
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Tesfay Gebreslassie Gebrehiwot,1 Haftea Hagos Mekonen,1 Tsegu Hailu Gebru,1 Kbrom Gmechu Kiros,1 Berhanu Gebresilassie,2 Guesh Teklu,1 Haileslassie Tesfay Tadese,1 Yared Haileslassie1 1Nursing Department, College of Medicine and Health Science, Adigrat ...
Gebreslassie Gebrehiwot T +7 more
doaj
The purpose of this paper is less to answer questions than to ask them, and less to define ‘carers’ than to understand who they are. In particular, its purpose is to ask why the label ‘family carer’ may be rejected by some of them, or by particular ...
Care Alliance Ireland
core +1 more source
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen +11 more
wiley +1 more source

