Results 81 to 90 of about 4,270,416 (296)

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Utilisation of postnatal care services among maternal in Maeen District – Sana’a City, Yemen

BMC Pregnancy and Childbirth
Background One of the most effective ways to reduce maternal and neonatal mortality is to improve mother and newborn health via the provision of appropriate postnatal care services by qualified healthcare providers.
Abdulnasser A. Haza’a, Marzoq A. Odhah, Saddam A. Al-Ahdal, Fawz M. Abol–Gaith, Nada A. Ismail, Mohammed S. Al-Awar, Abdulfatah S. Al-Jaradi, Wedian S. Eidah, Manar M. Kaid   +8 more
doaj   +1 more source

Expectations and experiences of hospital postnatal care in the UK: a systematic review of quantitative and qualitative studies

BMJ Open, 2019
Objectives To report on women’s and families’ expectations and experiences of hospital postnatal care, and also to reflect on women’s satisfaction with hospital postnatal care and to relate their expectations to their actual care experiences.Design ...
Reem Malouf, Jane Henderson, Fiona Alderdice   +2 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Seeking to explore what matters to women about postnatal care

, 2006
It is already known that for many women hospital postnatal care is the least satisfying and valued part of their maternity care provision (Audit Commission, 1997).
Wray, J
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The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care [PDF]

, 2015
Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important.
Downe, Soo, Symon, Andrew, Knapp, Rebecca, Rebecca Knapp, null null, Soo Downe, Peter Diggle, Whorwell, Peter; id_orcid, Andrew Symon, Kenneth William Finlayson, Finlayson, Kenneth William, Diggle, Peter   +11 more
core   +2 more sources

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Reducing the length of postnatal hospital stay: implications for cost and quality of care [PDF]

, 2016
Background  UK health services are under pressure to make cost savings while maintaining quality of care. Typically reducing the length of time patients stay in hospital and increasing bed occupancy are advocated to achieve service efficiency ...
Helen Cheyne, Bowers, John, Cheyne, Helen, John Bowers   +3 more
core   +2 more sources

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Analysis of Home Care Supports Funded by the HSE 2008–2016 [PDF]

, 2016
This paper seeks to summarise the situation of publicly funded home care over the period 2008- 2016. Of particular interest is the overall change to the level of resources being directed to home care in the 2016 HSE Service Plan, in particular the actual
Care Alliance Ireland
core