Results 91 to 100 of about 1,208,324 (319)

Efficacy and safety of sublingual buprenorphine in managing acute postoperative pain – A systematic review

Journal of Anaesthesiology Clinical Pharmacology
Sublingual (SL) buprenorphine has been used as a modality of managing acute postoperative pain in many studies. This systematic review aimed to investigate the safety and efficacy of SL buprenorphine as an analgesic for various surgeries.
Abhijit S. Nair, Ujjwalraj Dudhedia, Prasad Vilas Bodas, Manmohan Rangaiah, Nitinkumar Borkar   +4 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Postoperative delirium in liver resection patients: Usefulness of the abdominal wall fat index

, 2019
Postoperative delirium is one of the most common and important complications in patients who have undergone surgery. Although the precise mechanism of postoperative delirium is unclear, several risk factors have been reported.
Kugiyama, Tota, Imai, Ryo, Fujioka, Hikaru, Takeshita, Hiroaki, Kitasato, Amane, Maeda, Shigeto, Taniguchi, Ken, Hirayama, Takanori, Kuroki, Tamotsu, Tokunaga, Takayuki, Adachi, Toshiyuki   +10 more
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Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

The effect of Lidocaine on post-tonsillectomy pain In Children: A Triple-Blind Clinical Trial [PDF]

Introduction: Tonsillectomy is one of the most common surgical operations in children and has complications such as pain, hemorrhage, laryngospasm, postoperative nausea and vomiting.
محمدی, محمدعلی, علاف اکبری, سوره, عیسی زاده فر, خاطره, انتظاری, مسعود, پیرزاده, اکبر   +4 more
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Effects of aquatic exercises on upper limb physical function after a humeral shaft fracture – a time series analysis

Human Movement
Purpose Humeral shaft fractures account for 1.2% of all fractures in adults. Regardless of the treatment approach, the consequences of immobility can lead to decreased functional capacity in these individuals.
Pedro A.C. Silva, Eduarda H Santos, Paola Cobbo, Camila G. Miranda, Daniel B. Nampo, Shigueo B. Oda, Karen Obara, Jefferson R. Cardoso   +7 more
doaj   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Alkaline phosphatase predicts short-term postoperative outcome in adult patients with moyamoya disease

Frontiers in Neurology
BackgroundAlkaline phosphatase (ALP) has played a pivotal role in vascular diseases in recent years. However, the association between ALP level and postoperative complications of moyamoya disease (MMD) has not been studied.Patients and methodsBlood ...
Wei Sun, Huihui Wang, Qiheng He, Junsheng Li, Chenglong Liu, Zhiyao Zheng, Zhiyao Zheng, Siqi Mou, Siqi Mou, Bojian Zhang, Zhikang Zhao, Chuming Tao, Wei Liu, Xiangjun Shi, Xiangjun Shi, Yan Zhang, Peicong Ge, Peicong Ge, Dong Zhang, Dong Zhang, Jun Wu, Jun Wu   +21 more
doaj   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Preemptive Effect of Oral Pregabalin on Post-Operative Pain Control in Lower Limb Fractures [PDF]

Background & Objectives: dolnortnccnU postoperative pain can cause many adverse effects such as tachycardia, hypertension, myocardial ischemia, decreased alveolar ventilation and poor wound healing.
اخوان اکبری, قدرت, عیسی زاده فر, خاطره, میرزارحیمی, تیبا, انتظاری, مسعود   +3 more
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