Results 71 to 80 of about 1,332,869 (314)

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Free serum cortisol during the postoperative acute phase response determined by equilibrium dialysis liquid chromatography-tandem mass spectrometry [PDF]

, 2003
In severely ill patients low concentrations of the corticosteroid binding globulin are typically found; the aim of this study was to quantify directly free bioactive cortisol concentrations in the sera of postoperative cardiosurgical patients.
Küpper, Christina, Groetzner, Jan, Briegel, Josef, Vogeser, Michael   +3 more
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

The Infratrochlear Nerve Block Reduces the Incidence of Postoperative Nausea Vomiting in Pediatric Patients Undergoing Strabismus Surgery—A Retrospective Study

Biomedicines
Background/Objectives: Strabismus surgery in pediatric patients is associated with a high incidence of postoperative nausea and vomiting (PONV). Patients showing pain are more prone to develop PONV.
Chung-Sik Oh, Hyun Jin Shin, Seon-Ju Park, Seong-Hyop Kim, Yea-Ji Lee   +4 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Golden hour management in the patient with intraparenchymal cerebral hemorrhage: an Italian intersociety document

Journal of Anesthesia, Analgesia and Critical Care
Background Spontaneous intracerebral hemorrhage (ICH) accounts for 9–27% of all strokes worldwide and is associated with high mortality and disability. The main causes include vascular malformations, small- and large-vessel angiopathies, and coagulation ...
Gianluigi Morello, Daniela Alampi, Raffaele Aspide, Alessandra Beretta, Rita Bertuetti, Federico Bilotta, Etrusca Brogi, Giovanni Buscema, Anselmo Caricato, Davide Caruzzo, Carlo Alberto Castioni, Arturo Chieregato, Andrea Cortegiani, Alessandro De Cassai, Andrea Fabbri, Domenico Gelormini, Paolo Gritti, Lucrezia Guadrini, Alberto Librizzi, Nicola Latronico, Nicola Limbucci, Marina Munari, Edoardo Picetti, Giuseppina Pipitone, Gianluca Pucciarelli, Chiara Robba, Danilo Toni, Salvatore Sardo, Simone Maria Zerbi, Nicola Zugni, Frank Rasulo   +30 more
doaj   +1 more source

Recompression after percutaneous transforaminal endoscopic decompression for degenerative lumbar spinal stenosis: risk factors and outcomes of two different reoperation procedures

Frontiers in Surgery
PurposeTo determine the risk factors for recompression after percutaneous transforaminal endoscopic decompression (PTED) for the treatment of degenerative lumbar spinal stenosis (DLSS) and compare the outcomes of PTED and posterior lumbar interbody ...
Shuo Yuan, Aobo Wang, Ning Fan, Peng Du, Tianyi Wang, Jian Li, Wenyi Zhu, Lei Zang   +7 more
doaj   +1 more source

Efficacy of metoclopramide and dexamethasone for postoperative nausea and vomiting: a double-blind clinical trial [PDF]

Postoperative nausea and vomiting are common complications of anaesthesia. This double-blind clinical trial assessed the incidence of nausea and vomiting after cataract surgery with intravenous anaesthesia in 100 patients randomly assigned to ...
عیسی زاده فر, خاطره, اخوان اکبری, قدرت, انتظاری, مسعود, خوشباطن, منوچهر   +3 more
core   +1 more source

American Geriatrics Society Abstracted Clinical Practice Guideline for Postoperative Delirium in Older Adults [PDF]

, 2015
The abstracted set of recommendations presented here provides essential guidance both on the prevention of postoperative delirium in older patients at risk of delirium and on the treatment of older surgical patients with delirium, and is based on the ...
Adults, The American Geriatrics Society Expert Panel on Postoperative Delirium in Older
core   +1 more source