Results 51 to 60 of about 1,389,416 (314)

pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

Pharmacology Research & Perspectives, 2019
Despite intensive treatments including temozolomide (TMZ) administration, glioblastoma patient prognosis remains dismal and innovative therapeutic strategies are urgently needed.
Angélique Stéphanou, Annabelle Ballesta   +1 more
doaj   +1 more source

Spondylodiscitis: evaluation of patients in a tertiary hospital

Journal of Infection in Developing Countries, 2014
Introduction: Spondylodiscitis (SD) is an uncommon but important infection. The aim of this work was to study the risk factors, bacteriological features, clinical, laboratory and radiological findings of SD, and to shed light on the initial treatment ...
Safak Kaya, Serdar Ercan, Sehmuz Kaya, Ulas Aktas, Kagan Kamasak, Hakan Ozalp, Kadir Cinar, Recai Duymus, Mehmet Gazi Boyaci, Nesrin Akkoyun, Ahmet Emre Eskazan, Hakan Temiz   +11 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Thirty-day postoperative mortality after colorectal cancer surgery in England. [PDF]

, 2011
OBJECTIVES: To assess the variation in risk-adjusted 30-day postoperative mortality for patients with colorectal cancer between hospital trusts within the English NHS.
Quirke, Philip, Finan, Paul J, B. Rachet, E. F. Taylor, D. Forman, E. J. A. Morris, P. J. Finan, Thomas, James D, M. P. Coleman, Taylor, Elizabeth F, Forman, David, J. D. Thomas, Coleman, Michel P, P. Quirke, Rachet, Bernard, Morris, Eva JA   +15 more
core   +1 more source

Postoperative Tetanus [PDF]

Southern Medical Journal, 1910
n ...
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Patterns and frequency of anxiety in women undergoing gynaecological surgery [PDF]

, 2006
Patterns and frequency of anxiety in women undergoing gynaecological surgery Aims. Within a gynaecological surgical setting to identify the patterns and frequency of anxiety pre- and postoperatively; to identify any correlation between raised anxiety ...
Sandra Allen, Carr, Eloise C.J., Brockbank, Katrina, Paul Strike, Katrina Brockbank, Allen, Sandra, Eloise Carr, Strike, Paul   +7 more
core   +1 more source

Preoperative risk assessment and prehabilitation strategies in patients undergoing an esophagectomy for cancer resections: a single center retrospective analysis and a review of the literature

Frontiers in Anesthesiology
Esophagectomy remains being a surgical procedure with a high morbidity and mortality rate. Therefore, prehabilitation, defined as the group of interventions performed on the patient in the preoperative period to improve their functional capacity and ...
Silvia González Santos, Laura Martí Gelonch, Nuria González Jorrín, Mireia González Osinalde, Núria Rosell Romero   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Acute fatty liver disease in full-term pregnancy: a case report and review of the literature

Journal of Medical Case Reports
Background Cases of acute fatty liver of pregnancy are extremely rare but represent a serious complication as a life-threatening condition for both the mother and newborn in late-term pregnancy.
Phuc Nhon Nguyen, Quang Nhat Ho
doaj   +1 more source