Results 61 to 70 of about 661,738 (296)

Epidural analgesia is superior to local infiltration analgesia in children with cerebral palsy undergoing unilateral hip reconstruction

Acta Orthopaedica, 2016
Background and purpose — Treatment of postoperative pain in children with cerebral palsy (CP) is a major challenge. We investigated the effect of epidural analgesia, high-volume local infiltration analgesia (LIA), and an approximated placebo control on ...
Line Kjeldgaard Pedersen, Lone Nikolajsen, Ole Rahbek, Birgitte Uldall Duch, Bjarne Møller-Madsen   +4 more
doaj   +1 more source

Transcutaneous electrical nerve stimulation and analgesia following inguinal hernioplasties – Preliminary report

International Journal of Abdominal Wall and Hernia Surgery, 2019
INTRODUCTION: Inguinal hernioplasty is the most common surgical procedure. Although it is a low-risk surgery, it may present significant postoperative pain. Pharmacological pain relief may result in adverse effects.
Victoria Santa María, Magali Chahdi Beltrame, Sebastian Cirio, Federico Gorganchian   +3 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

Advanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li, Chengwei Zhang, Xinying Yu, Shuang Yao, Yiting Lai, Xiaozhu Sun, Yao Zhao, Xiaoyu Lan, Tingting Hu, Wenjin Li, Zhenzhen Ma, Huimin Ma, Zihan Wang, Haihai Liang, Jundong Jiao   +14 more
wiley   +1 more source

90% minimum effective concentration of ropivacaine for ultrasound-guided supra-inguinal fascia Iliaca compartment block for postoperative analgesia following total hip arthroplasty: a dose-finding study

BMC Anesthesiology
Background The ultrasound-guided supra-inguinal fascia iliaca compartment block (S-FICB) is a widely utilized regional anesthesia technique for postoperative pain management following total hip arthroplasty.
Yanping Zhang, Qin Zhang, Bo Guo, Liang Zhang   +3 more
doaj   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu, Haoli Wang, Jing Huang, Junhua Zhou, Jialong Hou, Hanwei Miao, Huixin Tan, Yining Wang, Hao Hu, Na Li, Pengcheng Qiu, Hongyu Zhang, Da He, Qingqing Wang   +13 more
wiley   +1 more source

Local infi ltration analgesia following total hip replacement: a review of current literature

Chinese Journal of Traumatology, 2014
【Abstract】Controlling postoperative pain after total hip replacement is important and controversy remains regarding different regimens. By reviewing 18 studies, we attempt to find whether local infiltration analgesia after total hip replacement has any ...
Gupta Tushar
doaj  

Ultrasound-Guided Paravertebral Block versus Caudal Epidural Block for Postoperative Analgesia in Pediatric Unilateral Inguinal Surgeries, A Prospective Randomized Double-Blind Study

Zagazig University Medical Journal
Background: Managing acute postoperative pain in pediatrics remains a clinical difficulty. Regional anesthetic modalities, specifically caudal epidural analgesia (CB) and paravertebral blockade (PVB), are frequently used to optimize postoperative ...
Ghada Hassan, Ayman Rady, Samira Ayad, Asmaa Salama   +3 more
doaj   +1 more source

Continuous epidural infusion of large concentration with small volume versus small concentration with large volume of levobupivacaine for postoperative analgesia after laparotomy: Effect of epidural levobupivacaine small versus large volume [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Introduction: Epidural analgesia after abdominal surgery is most effective mode of postoperative pain relief. Relative effects of the volume and concentration of local anaesthetic used for epidural analgesia are still under debate.
Solanki Vishal R., Patel Leena P., Gosai Nita   +2 more
doaj   +1 more source

The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy

, 2008
BACKGROUND: Patients undergoing total abdominal hysterectomy suffer significant postoperative pain. The transversus abdominis plane (TAP) block is a recently described approach to providing analgesia to the anterior abdominal wall.
Ochana, Alan, John G. McDonnell, McDonnell, John G., John G. Laffey, John Carney, Laffey, John G., Bhinder, Raj, Carney, John, Alan Ochana, Raj Bhinder   +9 more
core   +1 more source