Results 41 to 50 of about 498,713 (301)

Preoperative coping strategies and distress predict postoperative pain and morphine consumption in women undergoing abdominal gynecologic surgery [PDF]

open access: yes, 2005
Objectives The aim of the present study was to predict postoperative pain and morphine consumption based on preoperative psychosocial factors. Methods One hundred and twenty-two women completed measures of distress and coping 1 week before major ...
Fouladi, Rachel T.   +2 more
core  

The effects of indomethacin, diclofenac, and acetaminophen suppository on pain and opioids consumption after cesarean section [PDF]

open access: yes
Background: Cesarean section is one of the common surgeries of women. Acute post-operative pain is one of the recognized post-operative complications.
Masood Entezariasl   +7 more
core   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Analgesia pós-operatória: comparação entre cateter peridural e cateter na ferida operatória. [PDF]

open access: yes, 2009
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Brunharo, Guilherme Muriano
core  

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Postoperative opioid-free analgesia with acetaminophen and its impact on pain and postoperative nausea and vomiting following arthroscopic rotator cuff repair: a single-center retrospective study

open access: yesJournal of Pharmaceutical Health Care and Sciences
Background Opioids are commonly used for postoperative analgesia after arthroscopic rotator cuff repair; however, they pose an increased risk of postoperative nausea and vomiting. Therefore, multimodal analgesia using non-opioid analgesics is recommended.
Misa Okizuka   +6 more
doaj   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

Children's postoperative pro re nata (PRN) analgesia: nurses' administration practices

open access: yes, 2011
Aims and objectives: This paper reports a study aimed at exploring the nursing practices associated with the administration of pro re nata (PRN) postoperative analgesia to children, and at gaining a preliminary understanding of the decisions that nurses
Usher, Kim   +2 more
core   +2 more sources

Effectiveness of the erector spinae plane block for analgesia in lung resection surgery: a prospective randomized controlled trial

open access: yesМедицина неотложных состояний
Background. Lung resection procedures performed via a conventional thoracotomy are associated with substantial surgical trauma and pronounced postoperative pain.
A.P. Perkonos, I.I. Lisnyy
doaj   +1 more source

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