Results 31 to 40 of about 661,738 (296)

Patient-Controlled Epidural Analgesia (PCEA) Versus Intravenous Patient-Controlled Analgesia (IV PCA) for Acute Postoperative Pain Relief in Minimally Invasive Abdominal Surgeries: A Systematic Review [PDF]

, 2020
To reduce acute postoperative pain in major abdominal surgeries, patient-controlled epidural analgesia (PCEA) has been considered the gold standard. However, in recent years, its safety is being questioned as despite its low incidence rate of serious ...
Ahmad Yudianto, -, Junjungan Nimasratu Rahmatsani, -, Bambang Pujo Semedi, -, Christrijogo Sumartono Waloejo, -   +3 more
core   +1 more source

Children's postoperative pro re nata (PRN) analgesia: nurses' administration practices

, 2011
Aims and objectives: This paper reports a study aimed at exploring the nursing practices associated with the administration of pro re nata (PRN) postoperative analgesia to children, and at gaining a preliminary understanding of the decisions that nurses
Usher, Kim, Janelle Toombes, Wendy Smyth, Toombes, Janelle, Kim Usher, Smyth, Wendy   +5 more
core   +2 more sources

The efficacy and safety of paravertebral block for postoperative analgesia in renal surgery: A systematic review and meta-analysis of randomized controlled trials

Frontiers in Surgery, 2022
BackgroundParavertebral block (PVB) has been widely used in postoperative analgesia, especially in thoracic and breast surgery. However, the efficacy and safety of PVB for analgesia after renal surgery remains uncertain.
You Zhao, Yanan Kan, Xin Huang, Ming Wu, Weiping Luo, Jun Nie   +5 more
doaj   +1 more source

Comparing the Anaesthetic and Analgesic Efficacy of Caudal Levobupivacaine and Ropivacaine in Paediatric Patients [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Introduction of S enantiomer of bupivacaine is a major breakthrough in the history of local anaesthesia as the pharmacodynamics of these drugs were favourable in reducing the occurrence of cardiotoxicity, neurotoxicity and unintended motor ...
Sai Tejashree Veeravalli, BV Sunil, TV Shenoy   +2 more
doaj   +1 more source

Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8+T cell infiltration

Journal of Nanobiotechnology, 2023
Postoperative pain (POP) can promote tumor recurrence and reduce the cancer patient's quality of life. However, POP management has always been separated from tumor treatment in clinical practice, and traditional postoperative analgesia using opioids is ...
Mingxu Zhao, Shasha Zhu, Ding Zhang, Chang Zhou, Zhilai Yang, Chunhui Wang, Xuesheng Liu, Jiqian Zhang   +7 more
doaj   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

Advanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong, Bastien Schyrr, Stella Laperrousaz, Hritwick Banerjee, Andreas Leber, Fabien Sorin   +5 more
wiley   +1 more source

Quality of recovery and analgesia after total abdominal hysterectomy under general anesthesia: A randomized controlled trial of TAP block vs epidural analgesia vs parenteral medications

Journal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: Parenteral analgesics and epidural analgesia are two standard options to treat postoperative pain after total abdominal hysterectomy (TAH).
Preethy Mathew, Neelam Aggarwal, Kamlesh Kumari, Aakriti Gupta, Nidhi Panda, Rashmi Bagga   +5 more
doaj   +1 more source

Effects of dexmedetomidine as an adjuvant to ropivacaine or ropivacaine alone on duration of postoperative analgesia: A systematic review and meta-analysis of randomized controlled trials.

PLoS ONE, 2023
BackgroundRopivacaine is a long-acting local anesthetic that is used to treat postoperative pain. Adjuvant use of dexmedetomidine in regional anesthesia may prolong the duration of analgesia.
Fangzhou Li, Liang Guo, Zijin Huang, Fei Lin, Linghui Pan   +4 more
doaj   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source