Results 1 to 10 of about 139,014 (175)

Postoperative cognitive dysfunction—current research progress [PDF]

Frontiers in Behavioral Neuroscience
Postoperative cognitive dysfunction (POCD) commonly occurs after surgery, particularly in elderly individuals. It is characterized by a notable decline in cognitive performance, encompassing memory, attention, coordination, orientation, verbal fluency ...
Qi Zhao, Hui Wan, Hui Pan, Yiquan Xu
doaj   +3 more sources

Postoperative cognitive dysfunction: a concept analysis. [PDF]

Aging Clin Exp Res
Background Post-operative cognitive dysfunction (POCD) is a concern for clinicians that often presents post-surgery where generalized anesthesia has been used. Its prevalence ranges from 36.6% in young adults to 42.4% in older individuals.
Varpaei HA, Farhadi K, Mohammadi M, Khafaee Pour Khamseh A, Mokhtari T.   +4 more
europepmc   +4 more sources

Nanopathways modulating postoperative cognitive dysfunction: extracellular vesicles [PDF]

Frontiers in Cell and Developmental Biology
Postoperative cognitive dysfunction is a common central nervous system complication after general anesthesia in the elderly, and when it occurs, it will seriously affect the patient’s postoperative recovery and quality of life, which puts elderly ...
Yunmeng Zhang, Zengsheng Yin, Zhiyong Zou, Shangzhi Feng, Huayang Xu   +4 more
doaj   +2 more sources

Etiology and Pathogenesis of Postoperative Cognitive Dysfunction (Review)

Общая реаниматология, 2023
Impairment of higher mental functions can complicate the course of the postoperative period even after short and minimally invasive, including laparoscopic, surgical procedures.
M. I. Neimark, V. V. Shmelev, A. A. Rakhmonov, Z. A. Titova   +3 more
doaj   +2 more sources

The involvement of the gut microbiota in postoperative cognitive dysfunction based on integrated metagenomic and metabolomics analysis

Microbiology Spectrum, 2023
Cognitive dysfunction is a common symptom experienced by elderly individuals after surgery, resulting in memory problems, difficulties with logical thinking, hallucinations, delusions, and an increased risk of dementia.
Shi-hua Zhang, Xiao-yu Jia, Qing Wu, Jia Jin, Long-sheng Xu, Lei Yang, Jun-gang Han, Qing-he Zhou   +7 more
doaj   +2 more sources

Postoperative cognitive dysfunction

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
DOI：10.3969/j.issn.1672-6731.2010.04 ...
Cheng⁃shi XU, Yun YUE
doaj   +3 more sources

The role of dexmedetomidine administered via intravenous infusion as adjunctive therapy to mitigate postoperative delirium and postoperative cognitive dysfunction in elderly patients undergoing regional anesthesia: a meta-analysis of randomized controlled trials

BMC Anesthesiology
Study objective This meta-analysis aimed to assess whether continuous intravenous administration of DEX during surgery can be part of the measures to prevent the onset of postoperative delirium and postoperative cognitive dysfunction in elderly ...
Di Wang, Xiao He, Zicen Li, He Tao, Congjie Bi   +4 more
doaj   +2 more sources

Unraveling the role and mechanism of mitochondria in postoperative cognitive dysfunction: a narrative review. [PDF]

J Neuroinflammation
Postoperative cognitive dysfunction (POCD) is a frequent neurological complication encountered during the perioperative period with unclear mechanisms and no effective treatments.
Zhang Z, Yang W, Wang L, Zhu C, Cui S, Wang T, Gu X, Liu Y, Qiu P.   +8 more
europepmc   +2 more sources

Advances in the use of dexmedetomidine for postoperative cognitive dysfunction

Anesthesiology and Perioperative Science
Postoperative cognitive dysfunction, a common neurological complication in the perioperative period, seriously affects patient survival and prognosis. Its high incidence has made the study of postoperative cognitive dysfunction challenging.
Meng Deng, Yuan Wang, Beibei Zheng
doaj   +2 more sources

MEF2C Alleviates Postoperative Cognitive Dysfunction by Repressing Ferroptosis. [PDF]

CNS Neurosci Ther
Ferroptosis, a form of programmed cell death featured by lipid peroxidation, has been proposed as a potential etiology for postoperative cognitive dysfunction (POCD).
Wang S, Wu Z, Bu X, Peng X, Zhou Q, Song W, Gao W, Wang W, Xia Z.   +8 more
europepmc   +2 more sources