Results 21 to 30 of about 139,014 (175)

High postoperative serum cortisol level is associated with increased risk of cognitive dysfunction early after coronary artery bypass graft surgery: a prospective cohort study. [PDF]

open access: yesPLoS ONE, 2013
CONTEXT:Stress response induced by surgery is proposed to play an important role in the pathogenesis of postoperative cognitive dysfunction. OBJECTIVE:To investigate the association between postoperative serum cortisol level and occurrence of cognitive ...
Dong-Liang Mu   +7 more
doaj   +1 more source

Dysfunction of EAAT3 Aggravates LPS-Induced Post-Operative Cognitive Dysfunction

open access: yesMembranes, 2022
Numerous results have revealed an association between inhibited function of excitatory amino acid transporter 3 (EAAT3) and several neurodegenerative diseases.
Xiao-Yan Wang   +7 more
doaj   +1 more source

Dual roles of anesthetics in postoperative cognitive dysfunction: Regulation of microglial activation through inflammatory signaling pathways

open access: yesFrontiers in Immunology, 2023
Postoperative cognitive dysfunction (POCD) is a prevalent clinical entity following surgery and is characterized by declined neurocognitive function. Neuroinflammation mediated by microglia is the essential mechanism of POCD.
Mengxue Zhang, Yiqing Yin
semanticscholar   +1 more source

Postoperative delirium and cognitive dysfunction [PDF]

open access: yesBritish Journal of Anaesthesia, 2009
Postoperative delirium and cognitive dysfunction (POCD) are topics of special importance in the geriatric surgical population. They are separate entities, whose relationship has yet to be fully elucidated. Although not limited to geriatric patients, the incidence and impact of both are more profound in geriatric patients.
Stacie Deiner, Jeffrey H. Silverstein
openaire   +3 more sources

Relationship between postoperative biomarkers of neuronal injury and postoperative cognitive dysfunction: A meta-analysis

open access: yesPLoS ONE, 2023
Early biomarkers are needed to identify patients at risk of developing postoperative cognitive dysfunction (POCD). Our objective was to determine neuronal injury-related biomarkers with predictive values for this condition.
Xiaohua Wang   +9 more
semanticscholar   +1 more source

Effect of remote ischemic preconditioning on cognitive function after off-pump coronary artery bypass graft: a pilot study [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundSeveral studies have shown in animal models that remote ischemic preconditioning (rIPC) has a neuroprotective effect. However, a randomized controlled trial in human subjects to investigate the neuroprotective effect of rIPC after cardiac ...
Kyoung-Woon Joung   +8 more
doaj   +1 more source

Electroacupuncture pretreatment preserves telomerase reverse transcriptase function and alleviates postoperative cognitive dysfunction by suppressing oxidative stress and neuroinflammation in aged mice

open access: yesCNS Neuroscience & Therapeutics, 2023
Elderly patients often exhibit postoperative cognitive dysfunction (POCD), a postsurgical decline in memory and executive function. Oxidative stress and neuroinflammation, both pathological characteristics of the aged brain, contribute to this decline ...
Wen Wang   +7 more
semanticscholar   +1 more source

Postoperative Delirium and Postoperative Cognitive Dysfunction [PDF]

open access: yesAnesthesiology, 2019
Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Postoperative delirium and postoperative cognitive dysfunction share risk factors and may co-occur,
Nader D. Nader, Matthew Umholtz
openaire   +5 more sources

Downregulation of Nrf2 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Aged Rats by Sensitizing Oxidative Stress and Neuroinflammation

open access: yesOxidative Medicine and Cellular Longevity, 2023
Postoperative cognitive dysfunction (POCD) is a recognized clinical complication defined by a new cognitive impairment arising after a surgical procedure.
Liang Li, Fanqing Meng, Dongliang Li
semanticscholar   +1 more source

Does postoperative cognitive decline after coronary bypass affect quality of life?

open access: yesOpen Heart, 2021
Objective This study aimed to explore the influence of coronary artery bypass grafting (CABG) on both postoperative cognitive dysfunction and quality of life (QoL) and the association between the two patient-related outcomes.Methods In a prospective ...
Frederik Keus   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy